Cannabis use and mental illness: understanding circuit dysfunction through preclinical models
BW Jenkins, JY Khokhar - Frontiers in psychiatry, 2021 - frontiersin.org
Patients with a serious mental illness often use cannabis at higher rates than the general
population and are also often diagnosed with cannabis use disorder. Clinical studies reveal …
population and are also often diagnosed with cannabis use disorder. Clinical studies reveal …
Cannabinoid CB1 receptors regulate salivation
K Andreis, J Billingsley, K Naimi Shirazi… - Scientific reports, 2022 - nature.com
Saliva serves multiple important functions within the body that we typically take for granted,
such as helping prepare food for swallowing and defense against oral pathogens. Dry …
such as helping prepare food for swallowing and defense against oral pathogens. Dry …
How depression and antidepressant drugs affect endocannabinoid system?—review of clinical and preclinical studies
J Dragon, E Obuchowicz - Naunyn-Schmiedeberg's Archives of …, 2024 - Springer
As major depressive disorder is becoming a more and more common issue in modern
society, it is crucial to discover new possible grip points for its diagnosis and antidepressive …
society, it is crucial to discover new possible grip points for its diagnosis and antidepressive …
[HTML][HTML] Endocannabinoid system reactivity during stress processing in healthy humans
J Spohrs, M Prost, M Ulrich, PL Plener, L Bindila… - Biological …, 2022 - Elsevier
Stress underlies the development of various psychiatric disorders. Rodent studies suggest
an involvement of the endocannabinoid system in the modulation of the stress response …
an involvement of the endocannabinoid system in the modulation of the stress response …
[HTML][HTML] Clustering of cognitive phenotypes identifies susceptible and resilient offspring in a rat model of maternal immune activation and early-life stress
JM Lorusso, RM Woods, F McEwan, JD Glazier… - Brain, Behavior, & …, 2022 - Elsevier
Schizophrenia and other neurodevelopmental disorders often have very heterogeneous
symptoms, especially regarding cognition: while some individuals may exhibit deficient …
symptoms, especially regarding cognition: while some individuals may exhibit deficient …
Postpartum scarcity-adversity inflicts sex-specific cerebellar adaptations and reward behaviors in adolescence
M Maulik, K Looschen, C Smith, K Johnson… - Pharmacology …, 2023 - Elsevier
Early life adversity in the form of poor postnatal care is a major developmental stressor
impacting behavior later in life. Previous studies have shown the impact of early life stress …
impacting behavior later in life. Previous studies have shown the impact of early life stress …
Retinoic acid supplementation ameliorates motor incoordination via RARα-CBLN2 in the cerebellum of a prenatal valproic acid-exposed rat autism model
B Yuan, L Luo, C Hu, F Lin, T Yang, J Chen, T Li - Neuroscience Letters, 2023 - Elsevier
In addition to their core symptoms, most individuals with autism spectrum disorder (ASD)
also experience motor impairments. These impairments are often linked to the cerebellum …
also experience motor impairments. These impairments are often linked to the cerebellum …
Early life stress induces decreased expression of CB1R and FAAH and epigenetic changes in the medial prefrontal cortex of male rats
Several studies in both animal models and in humans have provided substantial evidence
that early life stress (ELS) induces long-term changes in behavior and brain function, making …
that early life stress (ELS) induces long-term changes in behavior and brain function, making …
Nicotine exposure during breastfeeding alters the expression of endocannabinoid system biomarkers in female but not in male offspring at adulthood
RA Miranda, VST Rodrigues, TC Peixoto… - … Origins of Health and …, 2023 - cambridge.org
Early nicotine exposure compromises offspring's phenotype at long-term in both sexes. We
hypothesize that offspring exposed to nicotine during breastfeeding show deregulated …
hypothesize that offspring exposed to nicotine during breastfeeding show deregulated …
Early Adversity Affects Cerebellar Structure and Function—A Systematic Review of Human and Animal Studies
Recent research has highlighted cerebellar involvement in cognition and several psychiatric
conditions such as mood and anxiety disorders and schizophrenia. Attention …
conditions such as mood and anxiety disorders and schizophrenia. Attention …