Adaptive deep brain stimulation (aDBS) controlled by local field potential oscillations
Despite their proven efficacy in treating neurological disorders, especially Parkinson's
disease, deep brain stimulation (DBS) systems could be further optimized to maximize …
disease, deep brain stimulation (DBS) systems could be further optimized to maximize …
Behavioral functions of the mesolimbic dopaminergic system: an affective neuroethological perspective
A Alcaro, R Huber, J Panksepp - Brain research reviews, 2007 - Elsevier
The mesolimbic dopaminergic (ML-DA) system has been recognized for its central role in
motivated behaviors, various types of reward, and, more recently, in cognitive processes …
motivated behaviors, various types of reward, and, more recently, in cognitive processes …
Reduction in subthalamic 8–35 Hz oscillatory activity correlates with clinical improvement in Parkinson's disease
Strong synchronization of neuronal activity occurs in the 8–35 Hz band in the subthalamic
nucleus (STN) of patients with Parkinson's disease (PD) and is evident as oscillatory local …
nucleus (STN) of patients with Parkinson's disease (PD) and is evident as oscillatory local …
Event‐related beta desynchronization in human subthalamic nucleus correlates with motor performance
Although the basal ganglia play an important role in self‐generated movement, their
involvement in externally paced voluntary movement is less clear. We recorded local field …
involvement in externally paced voluntary movement is less clear. We recorded local field …
Deep brain stimulation can suppress pathological synchronisation in parkinsonian patients
A Eusebio, W Thevathasan, LD Gaynor… - Journal of Neurology …, 2011 - jnnp.bmj.com
Background Although deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a
highly effective therapeutic intervention in severe Parkinson's disease, its mechanism of …
highly effective therapeutic intervention in severe Parkinson's disease, its mechanism of …
Resting oscillatory cortico-subthalamic connectivity in patients with Parkinson's disease
Both phenotype and treatment response vary in patients with Parkinson's disease.
Anatomical and functional imaging studies suggest that individual symptoms may represent …
Anatomical and functional imaging studies suggest that individual symptoms may represent …
Beta oscillatory activity in the subthalamic nucleus and its relation to dopaminergic response in Parkinson's disease
M Weinberger, N Mahant… - Journal of …, 2006 - journals.physiology.org
Recent studies suggest that beta (15–30 Hz) oscillatory activity in the subthalamic nucleus
(STN) is dramatically increased in Parkinson's disease (PD) and may interfere with …
(STN) is dramatically increased in Parkinson's disease (PD) and may interfere with …
Rhythm-specific pharmacological modulation of subthalamic activity in Parkinson's disease
The subthalamic nucleus (STN) has a key role in the pathophysiology of Parkinson's
disease and is the primary target for high-frequency deep brain stimulation (DBS). The STN …
disease and is the primary target for high-frequency deep brain stimulation (DBS). The STN …
Basal ganglia local field potential activity: character and functional significance in the human
P Brown, D Williams - Clinical neurophysiology, 2005 - Elsevier
Functional neurosurgery in patients with movement disorders has provided a unique
opportunity to record directly form the human basal ganglia (BG) and to thereby further our …
opportunity to record directly form the human basal ganglia (BG) and to thereby further our …
Subthalamic span of β oscillations predicts deep brain stimulation efficacy for patients with Parkinson's disease
The significance of oscillations that characterize the subthalamic nucleus in Parkinson's
disease is still under debate. Here, we analysed the spectral and spatial characteristics of …
disease is still under debate. Here, we analysed the spectral and spatial characteristics of …