Recent developments in natural biopolymer based drug delivery systems
Targeted delivery of drug molecules to diseased sites is a great challenge in pharmaceutical
and biomedical sciences. Fabrication of drug delivery systems (DDS) to target and/or …
and biomedical sciences. Fabrication of drug delivery systems (DDS) to target and/or …
Metallic nanoparticles as drug delivery system for the treatment of cancer
Introduction The targeted delivery of anticancer agents to tumor is a major challenge
because most of the drugs show off-target effect resulting in nonspecific cell death …
because most of the drugs show off-target effect resulting in nonspecific cell death …
A review of small molecules and drug delivery applications using gold and iron nanoparticles
Conventional cancer treatment techniques show several limitations including low or no
specificity and consequently a low efficacy in discriminating between cancer cells and …
specificity and consequently a low efficacy in discriminating between cancer cells and …
Emerging nanotechnology-based therapeutics to combat multidrug-resistant cancer
Cancer often develops multidrug resistance (MDR) when cancer cells become resistant to
numerous structurally and functionally different chemotherapeutic agents. MDR is …
numerous structurally and functionally different chemotherapeutic agents. MDR is …
Nanotherapeutics approaches to overcome P-glycoprotein-mediated multi-drug resistance in cancer
Multidrug resistance (MDR) in cancer chemotherapy is a growing concern for medical
practitioners. P-glycoprotein (P-gp) overexpression is one of the major reasons for multidrug …
practitioners. P-glycoprotein (P-gp) overexpression is one of the major reasons for multidrug …
Role of multidrug resistance-associated proteins in cancer therapeutics: past, present, and future perspectives
Cancer, a major public health problem, is one of the world's top leading causes of death.
Common treatments for cancer include cytotoxic chemotherapy, surgery, targeted drugs …
Common treatments for cancer include cytotoxic chemotherapy, surgery, targeted drugs …
Effect of cellular and microenvironmental multidrug resistance on tumor-targeted drug delivery in triple-negative breast cancer
O Tezcan, AS Elshafei, K Benderski, E Rama… - Journal of Controlled …, 2023 - Elsevier
Multidrug resistance (MDR) reduces the efficacy of chemotherapy. Besides inducing the
expression of drug efflux pumps, chemotherapy treatment alters the composition of the tumor …
expression of drug efflux pumps, chemotherapy treatment alters the composition of the tumor …
Epigallocatechin gallate-gold nanoparticles exhibit superior antitumor activity compared to conventional gold nanoparticles: Potential synergistic interactions
Epigallocatechin gallate (EGCG) possesses significant antitumor activity and binds to
laminin receptors, overexpressed on cancer cells, with high affinity. Gold nanoparticles …
laminin receptors, overexpressed on cancer cells, with high affinity. Gold nanoparticles …
MDR in cancer: Addressing the underlying cellular alterations with the use of nanocarriers
Multidrug resistance (MDR) is associated with a wide range of pathological changes at
different cellular and intracellular levels. Nanoparticles (NPs) have been extensively …
different cellular and intracellular levels. Nanoparticles (NPs) have been extensively …
Gold nanoparticle‑mediated delivery of paclitaxel and nucleic acids for cancer therapy
Z Wang, J Dong, Q Zhao, Y Ying… - Molecular …, 2020 - spandidos-publications.com
Paclitaxel is a potent antineoplastic agent, but poor solubility and resistance have limited its
use. Gold nanoparticles (AuNPs) are widely studied as drug carriers because they can be …
use. Gold nanoparticles (AuNPs) are widely studied as drug carriers because they can be …