Anorexia is part of the body's acute-phase response to illness. Microbial products such as
lipopolysaccharides (LPS), which are also commonly used to model acute illness, trigger the …

The cytokine IL-6 plays a protective role in immune responses against bacterial infections.
However, the mechanisms of IL-6–mediated protection are only partially understood. IL-6 …

Campylobacter jejuni is an important enteric pathogen that causes diarrheas of different
degrees of severity and several extra-intestinal manifestations, including Guillain-Barre …

Background: Campylobacter jejuni can cause a spectrum of diseases in humans, ranging
from enteritis and diarrhoea to severe inflammation, profuse bloody diarrhoea and chronic …

Despite years of research and clinical advances, chronic pulmonary infections with mucoid
Pseudomonas aeruginosa remain the primary concern for cystic fibrosis patients. Much of …

OBJECTIVE: Oral lichen planus (OLP) is chronic inflammatory disease of the oral mucosa,
presenting in various clinical forms. The etiology of OLP is still unknown but mounting …

Sialoadhesin (Sn) is a macrophage (Mϕ)-restricted receptor that recognizes sialylated
ligands on host cells and pathogens. Although Sn is thought to be important in cellular …

Neuroinflammation results in dysregulation of serotonergic neurons in the dorsal raphe
nucleus (doR) and is considered to play an important role in the pathophysiology of …

Enteric pathogens are constantly exposed to stressful conditions in their natural habitat in
the host and even more in the extra-host environment, including food processing. The aim of …

Introduction Novel preventive strategies in periodontal disease target the bacterial-induced
inflammatory host response to reduce associated tissue destruction. Strategies focus on the …