Anticholinergic burden quantified by anticholinergic risk scales and adverse outcomes in older people: a systematic review
Background The cumulative effect of taking multiple medicines with anticholinergic
properties termed as anticholinergic burden can adversely impact cognition, physical …
properties termed as anticholinergic burden can adversely impact cognition, physical …
Anticholinergic drug burden tools/scales and adverse outcomes in different clinical settings: a systematic review of reviews
TJ Welsh, V van der Wardt, G Ojo, AL Gordon… - Drugs & aging, 2018 - Springer
Background Cumulative anticholinergic exposure (anticholinergic burden) has been linked
to a number of adverse outcomes. To conduct research in this area, an agreed approach to …
to a number of adverse outcomes. To conduct research in this area, an agreed approach to …
Polypharmacy among adults aged 65 years and older in the United States: 1988–2010
CJ Charlesworth, E Smit, DSH Lee… - … Series A: Biomedical …, 2015 - academic.oup.com
Background. Older adults frequently have several chronic health conditions which require
multiple medications. We illustrated trends in prescription medication use over 20 years in …
multiple medications. We illustrated trends in prescription medication use over 20 years in …
Prevalence of potentially inappropriate medication use in older adults using the 2012 Beers criteria
AJ Davidoff, GE Miller, EM Sarpong… - Journal of the …, 2015 - Wiley Online Library
Objectives To use the most recently available population‐based data to estimate potentially
inappropriate medication (PIM) prevalence under the 2012 update of the Beers list of PIM s …
inappropriate medication (PIM) prevalence under the 2012 update of the Beers list of PIM s …
Comparison of anticholinergic risk scales and associations with adverse health outcomes in older people
MS Salahudeen, SN Hilmer… - Journal of the American …, 2015 - Wiley Online Library
Objectives To investigate whether anticholinergic burden scores from nine published
anticholinergic scales are associated with adverse health outcomes, including hospital …
anticholinergic scales are associated with adverse health outcomes, including hospital …
Drug Burden Index in older adults: theoretical and practical issues
Anticholinergic and sedative medications are commonly used in older adults and are
associated with adverse clinical outcomes. The Drug Burden Index was developed to …
associated with adverse clinical outcomes. The Drug Burden Index was developed to …
DEFEAT-polypharmacy: deprescribing anticholinergic and sedative medicines feasibility trial in residential aged care facilities
Background Prolonged use of anticholinergic and sedative medicines is correlated with
worsening cognition and physical function decline. Deprescribing is a proposed intervention …
worsening cognition and physical function decline. Deprescribing is a proposed intervention …
Quantifying anticholinergic burden and sedative load in older adults with polypharmacy: a systematic review of risk scales and models
SB Al Rihani, M Deodhar, LI Darakjian, P Dow… - Drugs & aging, 2021 - Springer
Background Patients taking medication with high anticholinergic and sedative properties are
at increased risk of experiencing poor cognitive and physical outcomes. Therefore, precise …
at increased risk of experiencing poor cognitive and physical outcomes. Therefore, precise …
Quality of anticholinergic burden scales and their impact on clinical outcomes: a systematic review
A Lisibach, V Benelli, MG Ceppi… - European journal of …, 2021 - Springer
Purpose Older people are at risk of anticholinergic side effects due to changes affecting drug
elimination and higher sensitivity to drug's side effects. Anticholinergic burden scales (ABS) …
elimination and higher sensitivity to drug's side effects. Anticholinergic burden scales (ABS) …
The association between anticholinergic medication burden and health related outcomes in the 'oldest old': a systematic review of the literature
K Cardwell, CM Hughes, C Ryan - Drugs & aging, 2015 - Springer
Background Increased exposure to anticholinergic medication is problematic, particularly in
those aged 80 years and older. Objective The aim of this systematic review was to identify …
those aged 80 years and older. Objective The aim of this systematic review was to identify …