Poly (A) tails have long been known as stable 3′ modifications of eukaryotic mRNAs,
added during nuclear pre‐mRNA processing. It is now appreciated that this modification is …

Poly (A) tails are found at the 3′ ends of almost all eukaryotic mRNAs. They are bound by
two different poly (A) binding proteins, PABPC in the cytoplasm and PABPN1 in the nucleus …

In animal oocytes and early embryos, mRNA poly (A)-tail length strongly influences
translational efficiency (TE), but later in development this coupling between tail length and …

DAZL proteins are germ‐cell‐specific RNA‐binding proteins essential for gametogenesis.
The precise molecular role of these proteins in germ‐cell development remains enigmatic; …

Abstract Poly (A)-binding proteins (PABPs) are central to the regulation of messenger RNA
(mRNA) translation and stability; however, the roles and contributions of different PABP …

In the present review, we describe the history of the identification of the eukaryotic
translation termination factors eRF1 and eRF3. As in the case of several proteins involved in …

PABPs [poly (A)-binding proteins] bind to the poly (A) tail of eukaryotic mRNAs and are
conserved in species ranging from yeast to human. The prototypical cytoplasmic member …

Abstract The mRNA 3′ poly (A) tail plays a critical role in regulating both mRNA translation
and turnover. It is bound by the cytoplasmic poly (A) binding protein (PABPC), an …

Gametogenesis is a highly complex process that requires the exquisite temporal, spatial and
amplitudinal regulation of gene expression at multiple levels. Translational regulation is …

Nonsense-mediated mRNA decay (NMD) is one of three regulatory mechanisms that
monitor the cytoplasm for aberrant mRNAs. NMD is usually triggered by premature …