[HTML][HTML] Intestinal glucagon-like peptide-1 effects on food intake: Physiological relevance and emerging mechanisms

JP Krieger - Peptides, 2020 - Elsevier
The gut-brain hormone glucagon-like peptide-1 (GLP-1) has received immense attention
over the last couple of decades for its widespread metabolic effects. Notably, intestinal GLP …

What is GLP-1 really doing in obesity?

T Hira, J Pinyo, H Hara - Trends in Endocrinology & Metabolism, 2020 - cell.com
Glucagon-like peptide-1 (GLP-1) is a gastrointestinal hormone released in response to meal
ingestion and enhances insulin secretion from pancreatic β cells. In several human studies …

Calcium signaling pathways: key pathways in the regulation of obesity

Z Song, Y Wang, F Zhang, F Yao, C Sun - International journal of …, 2019 - mdpi.com
Nowadays, high epidemic obesity-triggered hypertension and diabetes seriously damage
social public health. There is now a general consensus that the body's fat content exceeding …

Nobiletin ameliorates high fat-induced disruptions in rhythmic glucagon-like peptide-1 secretion

A Martchenko, AD Biancolin, SE Martchenko… - Scientific Reports, 2022 - nature.com
The incretin hormone glucagon-like peptide-1 (GLP-1) is secreted by the intestinal L cell in
response to nutrient intake. However, GLP-1 secretion also follows a circadian rhythm which …

Revisiting the concept of incretin and enteroendocrine L-cells as type 2 diabetes mellitus treatment

KH Lok, NJ Wareham, RS Nair, CW How… - Pharmacological …, 2022 - Elsevier
The significant growth in type 2 diabetes mellitus (T2DM) prevalence strikes a common
threat to the healthcare and economic systems globally. Despite the availability of several …

Improvement of glucose tolerance by food factors having glucagon-like peptide-1 releasing activity

T Hira, A Trakooncharoenvit, H Taguchi… - International Journal of …, 2021 - mdpi.com
Glucagon-like peptide-1 (GLP-1) is a gastrointestinal hormone released from
enteroendocrine L cells in response to meal ingestion. GLP-1 receptor agonists and GLP-1 …

A combination of glucagon-like peptide-1 receptor agonist and dietary intervention could Be a promising approach for obesity treatment

CY Lee - Frontiers in Endocrinology, 2021 - frontiersin.org
Obesity continues to be a global health issue. According to the World Health Organization
(WHO), its prevalence has increased almost 3-fold between 1975 and 2016; thirteen percent …

Combination of α-glycosyl-isoquercitrin and soybean fiber promotes quercetin bioavailability and glucagon-like peptide-1 secretion and improves glucose …

A Trakooncharoenvit, H Hara, T Hira - Journal of Agricultural and …, 2021 - ACS Publications
This study examined the effects of a combination of soybean fiber and α-glycosyl-
isoquercitrin (AGIQ) on improving quercetin bioavailability and glucose metabolism in rats …

Diet-induced obesity enhances postprandial glucagon-like peptide-1 secretion in Wistar rats, but not in diabetic Goto-Kakizaki rats

J Pinyo, H Hara, T Hira - British journal of nutrition, 2021 - cambridge.org
Glucagon-like peptide-1 (GLP-1) is postprandially secreted from enteroendocrine L-cells
and enhances insulin secretion. Currently, it is still controversial whether postprandial GLP-1 …

S-nitrosoglutathione reverts dietary sucrose-induced insulin resistance

I Sousa-Lima, AB Fernandes, RS Patarrão, YB Kim… - Antioxidants, 2020 - mdpi.com
The liver is a fundamental organ to ensure whole-body homeostasis, allowing for a proper
increase in insulin sensitivity from the fast to the postprandial status. Hepatic regulation of …