The new neurometabolic cascade of concussion

CC Giza, DA Hovda - Neurosurgery, 2014 - journals.lww.com
Since the original descriptions of postconcussive pathophysiology, there has been a
significant increase in interest and ongoing research to study the biological underpinnings of …

Mechanics of the brain: perspectives, challenges, and opportunities

A Goriely, MGD Geers, GA Holzapfel… - … and modeling in …, 2015 - Springer
The human brain is the continuous subject of extensive investigation aimed at
understanding its behavior and function. Despite a clear evidence that mechanical factors …

Chronic traumatic encephalopathy in blast-exposed military veterans and a blast neurotrauma mouse model

LE Goldstein, AM Fisher, CA Tagge, XL Zhang… - Science translational …, 2012 - science.org
Blast exposure is associated with traumatic brain injury (TBI), neuropsychiatric symptoms,
and long-term cognitive disability. We examined a case series of postmortem brains from US …

Military‐related traumatic brain injury and neurodegeneration

AC McKee, ME Robinson - Alzheimer's & Dementia, 2014 - Wiley Online Library
Mild traumatic brain injury (mTBI) includes concussion, subconcussion, and most exposures
to explosive blast from improvised explosive devices. mTBI is the most common traumatic …

Response of the cerebral vasculature following traumatic brain injury

A Salehi, JH Zhang, A Obenaus - Journal of Cerebral Blood …, 2017 - journals.sagepub.com
The critical role of the vasculature and its repair in neurological disease states is beginning
to emerge particularly for stroke, dementia, epilepsy, Parkinson's disease, tumors and …

The mechanics of traumatic brain injury: a review of what we know and what we need to know for reducing its societal burden

DF Meaney, B Morrison… - Journal of …, 2014 - asmedigitalcollection.asme.org
Traumatic brain injury (TBI) is a significant public health problem, on pace to become the
third leading cause of death worldwide by 2020. Moreover, emerging evidence linking …

Engineering cell alignment in vitro

Y Li, G Huang, X Zhang, L Wang, Y Du, TJ Lu… - Biotechnology …, 2014 - Elsevier
Cell alignment plays a critical role in various cell behaviors including cytoskeleton
reorganization, membrane protein relocation, nucleus gene expression, and ECM …

Brain neurotrauma: molecular, neuropsychological, and rehabilitation aspects

FH Kobeissy - 2015 - books.google.com
With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Traumatic brain injury and the neuronal microenvironment: a potential role for neuropathological mechanotransduction

MA Hemphill, S Dauth, CJ Yu, BE Dabiri, KK Parker - Neuron, 2015 - cell.com
Traumatic brain injury (TBI) is linked to several pathologies for which there is a lack of
understanding of disease mechanisms and therapeutic strategies. To elucidate injury …

Vascular smooth muscle cell dysfunction in neurodegeneration

G Hayes, J Pinto, SN Sparks, C Wang, S Suri… - Frontiers in …, 2022 - frontiersin.org
Vascular smooth muscle cells (VSMCs) are the key moderators of cerebrovascular dynamics
in response to the brain's oxygen and nutrient demands. Crucially, VSMCs may provide a …