Large vessel giant cell arteritis

KSM van der Geest, M Sandovici, TA Bley… - The Lancet …, 2024 - thelancet.com
Giant cell arteritis is the principal form of systemic vasculitis affecting people over 50. Large-
vessel involvement, termed large vessel giant cell arteritis, mainly affects the aorta and its …

[HTML][HTML] Impaired IL-6-induced JAK-STAT signaling in CD4+ T cells associates with longer treatment duration in giant cell arteritis

I Esen, M Sandovici, P Heeringa, AMH Boots… - Journal of …, 2024 - Elsevier
Abstract Introduction The IL-12-IFNγ-Th1 and the IL-6-IL-23-Th17 axes are considered the
dominant pathogenic pathways in Giant Cell Arteritis (GCA). Both pathways signal via …