Dexmedetomidine (DEX) is a highly selective and potent α2-adrenoceptor (α2-AR) agonist
that is widely used as a clinical anesthetic to induce anxiolytic, sedative, and analgesic …

This meta-analysis aimed to assess the clinical association of the preoperative prognostic
nutritional index (pre-PNI) with the risk of postoperative acute kidney injury. Four databases …

BACKGROUND: Renal ischemia and reperfusion (IR) contribute to perioperative acute
kidney injury, and oxygen is a key regulator of this process. We hypothesized that oxygen …

Background: Perioperative acute kidney injury (AKI) is common in surgical patients and is
associated with high morbidity and mortality. There are currently few options for AKI …

INTRODUCTION Acute kidney injury (AKI) is common in the perioperative period and is
associated with increased duration of hospitalization, infection rate, cost, and death [1]. It …

Introduction: Perioperative alterations in perfusion lead to ischemia and reperfusion injury,
and supplemental oxygen is administered during surgery to limit hypoxic injury but can lead …

Acute kidney injury (AKI) is a serious postoperative complication that affects a substantial
number of patients undergoing surgery (the specific incidence varies according to the …

Respiratory failure refers to pulmonary ventilation and ventilatory dysfunction caused by
various reasons, which makes the patient unable to maintain the gas exchange required for …

Many processes surrounding surgery can influence the oxygen supply or consumption of
organs. This thesis aimed to gain insight into a measurement method that can non …

Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly used in postoperative pain
management as part of multimodal analgesia. NSAIDs provide substantial analgesic efficacy …