Microbial signatures of health, gingivitis, and periodontitis

L Abusleme, A Hoare, BY Hong, PI Diaz - Periodontology 2000, 2021 - Wiley Online Library
The subgingival crevice harbors diverse microbial communities. Shifts in the composition of
these communities occur with the development of gingivitis and periodontitis, which are …

The oral microbiota: dynamic communities and host interactions

RJ Lamont, H Koo, G Hajishengallis - Nature reviews microbiology, 2018 - nature.com
The dynamic and polymicrobial oral microbiome is a direct precursor of diseases such as
dental caries and periodontitis, two of the most prevalent microbially induced disorders …

Microenvironment-responsive metal-phenolic nanozyme release platform with antibacterial, ROS scavenging, and osteogenesis for periodontitis

Y Xu, Y Luo, Z Weng, H Xu, W Zhang, Q Li, H Liu… - ACS …, 2023 - ACS Publications
Periodontitis is a chronic inflammatory disease deriving from dental plaque, characterized by
the excessive accumulation of reactive oxygen species (ROS), matrix metalloproteinase …

Polymicrobial communities in periodontal disease: Their quasi‐organismal nature and dialogue with the host

G Hajishengallis, RJ Lamont - Periodontology 2000, 2021 - Wiley Online Library
In health, indigenous polymicrobial communities at mucosal surfaces maintain an ecological
balance via both inter‐microbial and host‐microbial interactions that promote their own and …

Roles of Porphyromonas gingivalis and its virulence factors in periodontitis

W Xu, W Zhou, H Wang, S Liang - Advances in protein chemistry and …, 2020 - Elsevier
Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival
inflammation and bone loss. Periodontitis is associated with various systemic diseases …

Oral polymicrobial communities: Assembly, function, and impact on diseases

G Hajishengallis, RJ Lamont, H Koo - Cell host & microbe, 2023 - cell.com
Oral microbial communities assemble into complex spatial structures. The sophisticated
physical and chemical signaling systems underlying the community enable their collective …

The structure of dental plaque microbial communities in the transition from health to dental caries and periodontal disease

AM Valm - Journal of molecular biology, 2019 - Elsevier
The human oral cavity harbors diverse communities of microbes that live as biofilms: highly
ordered, surface-associated assemblages of microbes embedded in an extracellular matrix …

Role of Porphyromonas gingivalis in oral and orodigestive squamous cell carcinoma

RJ Lamont, ZR Fitzsimonds, H Wang… - Periodontology …, 2022 - Wiley Online Library
Oral and esophageal squamous cell carcinomas harbor a diverse microbiome that differs
compositionally from precancerous and healthy tissues. Though causality is yet to be …

Oral commensal streptococci: gatekeepers of the oral cavity

JJ Baty, SN Stoner, JA Scoffield - Journal of Bacteriology, 2022 - Am Soc Microbiol
Oral commensal streptococci are primary colonizers of the oral cavity. These streptococci
produce many adhesins, metabolites, and antimicrobials that modulate microbial succession …

An injectable and thermosensitive hydrogel: Promoting periodontal regeneration by controlled-release of aspirin and erythropoietin

X Xu, Z Gu, X Chen, C Shi, C Liu, M Liu, L Wang… - Acta biomaterialia, 2019 - Elsevier
Periodontitis is an inflammatory disease induced by complex interactions between host
immune system and plaque microorganism. Alveolar bone resorption caused by …