Two-component systems reprogramme diverse aspects of microbial physiology in response
to environmental cues. Canonical systems are composed of a transmembrane sensor …

To exist in a wide range of environmental niches, bacteria must sense and respond to a
variety of external signals. A primary means by which this occurs is through two-component …

Success in nature depends upon an ability to perceive and adapt to the surrounding
environment. Bacteria are not an exception; they recognize and constantly adjust to …

The past two decades have seen a worldwide resurgence in infections caused by
Treponema pallidum subsp. pallidum, the syphilis spirochete. The well-recognized capacity …

An appropriate response and adaptation to hyperosmolarity, ie., an external osmolarity that
is higher than the physiological range, can be a matter of life or death for all cells. It is …

Histidine kinases (HKs) are major players in bacterial signaling. There has been an
explosion of new HK crystal structures in the last 5 years. We globally analyze the structures …

The Logic of Chance offers a reappraisal and a new synthesis of theories, concepts, and
hypotheses on the key aspects of the evolution of life on earth in light of comparative …

Gene expression occurs in two essential steps: transcription and translation. In bacteria, the
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …

Continuous contamination of the environment with xenobiotics and related recalcitrant
compounds has emerged as a serious pollution threat. Bioremediation is the key to …

Listeria monocytogenes are Gram-positive, facultatively anaerobic, non-spore-forming
bacteria that easily adapt to changing environmental conditions. The ability to grow at a wide …