Recent developments in ring opening polymerization of lactones for biomedical applications

AC Albertsson, IK Varma - Biomacromolecules, 2003 - ACS Publications
Aliphatic polyesters prepared by ring-opening polymerization of lactones are now used
worldwide as bioresorbabale devices in surgery (orthopaedic devices, sutures, stents, tissue …

Biodegradable stents for coronary artery disease treatment: Recent advances and future perspectives

T Hu, C Yang, S Lin, Q Yu, G Wang - Materials Science and Engineering: C, 2018 - Elsevier
Cardiovascular diseases are one of the major causes of human death in the world.
Endovascular stents are the most important implantation devices in cardiovascular …

Long-term biocompatibility of a corrodible peripheral iron stent in the porcine descending aorta

M Peuster, C Hesse, T Schloo, C Fink, P Beerbaum… - Biomaterials, 2006 - Elsevier
Currently there are no biodegradable stents available for treatment of vascular obstructions
in patients with congenital heart defects. This study was performed to evaluate the safety of a …

Drug-releasing implants: current progress, challenges and perspectives

A Santos, MS Aw, M Bariana, T Kumeria… - Journal of Materials …, 2014 - pubs.rsc.org
The need for more efficient drug delivery strategies to treat resilient diseases and the rise of
micro and nanotechnology have led to the development of more sophisticated drug …

Controlled release of sirolimus from a multilayered PLGA stent matrix

X Wang, SS Venkatraman, FYC Boey, JSC Loo, LP Tan - Biomaterials, 2006 - Elsevier
The release of sirolimus from a bi-layer biodegradable polymeric film is reported in this
study. Approved drug-eluting metal stents use a thin polymer coating to control drug release …

Biodegradable stents with elastic memory

SS Venkatraman, LP Tan, JFD Joso, YCF Boey… - Biomaterials, 2006 - Elsevier
This work reports, for the first time, the development of a fully biodegradable polymeric stent
that can self-expand at body temperatures (∼ 37° C), using the concept of elastic memory …

Computational and experimental investigation into mechanical performances of Poly-L-Lactide Acid (PLLA) coronary stents

Q Wang, G Fang, Y Zhao, G Wang, T Cai - Journal of the mechanical …, 2017 - Elsevier
Abstract Poly-L-lactide Acid (PLLA), as a credible biodegradable polymer-based material,
can provide a promising amount of degradation time for vessel remodeling. Served as a sort …

Materiomics: An ‐omics Approach to Biomaterials Research

SW Cranford, J de Boer, C van Blitterswijk… - Advanced …, 2013 - Wiley Online Library
The past fifty years have seen a surge in the use of materials for clinical application, but in
order to understand and exploit their full potential, the scientific complexity at both sides of …

Thermo-induced shape-memory PEG-PCL copolymer as a dual-drug-eluting biodegradable stent

CS Yang, HC Wu, JS Sun, HM Hsiao… - ACS applied materials …, 2013 - ACS Publications
In this work, a thermo-induced shape-memory drug-eluting stent (SMDES) has been
developed by cross-linking PEG-PCL copolymer (cPEG-PCL). The stent is able to perform …

Ductile electroactive biodegradable hyperbranched polylactide copolymers enhancing myoblast differentiation

M Xie, L Wang, B Guo, Z Wang, YE Chen, PX Ma - Biomaterials, 2015 - Elsevier
Myotube formation is crucial to restoring muscular functions, and biomaterials that enhance
the myoblast differentiation into myotubes are highly desirable for muscular repair. Here, we …