Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …

Depression is one of the leading causes of disability, and, if left unmanaged, it can increase
the risk for suicide. The evidence base on the determinants of depression is fragmented …

Despite numerous studies on the neurobiology of depression, the etiological and
pathophysiological mechanisms of this disorder remain poorly understood. A large number …

Major depressive disorder (MDD) is currently the main cause of disability worldwide, but its
pathophysiology remains largely unknown, especially given its high heterogeneity in terms …

Worldwide, the incidence of major depressive disorder (MDD) is increasing annually,
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …

Speech carries essential information about the speaker's physiology and possible
pathophysiological conditions. Bio-acoustic voice qualities show promising value for …

Major depression (MD) is a complex, heterogeneous neuropsychiatric disorder. An early
age at onset of major depression (AAO-MD) has been associated with more severe illness …

Major depressive disorder (MDD) is a common mental disorder generally characterized by
symptoms associated with mood, pleasure and effectiveness in daily life activities. MDD is …

Nutrition and metabolism modify epigenetic signatures like histone acetylation and DNA
methylation. Histone acetylation and DNA methylation in the central nervous system (CNS) …

Identifying modifiable risk factors early on is essential to prevent major depressive disorder
(MDD). This study systematically investigated the causal relationship between 19 modifiable …