miRNA: a promising therapeutic target in cancer

A Menon, N Abd-Aziz, K Khalid, CL Poh… - International journal of …, 2022 - mdpi.com
microRNAs are small non-coding RNAs that regulate several genes post-transcriptionally by
complementarity pairing. Since discovery, they have been reported to be involved in a …

miRNAs driving diagnosis, progression, and drug resistance in multiple myeloma

MA Elkady, AM Yehia, EGE Elsakka… - … -Research and Practice, 2023 - Elsevier
Multiple myeloma (MM) is a tumor of transformed plasma cells. It's the second most common
hematologic cancer after non-Hodgkin lymphoma. MM is a complex disease with many …

MicroRNA: function, detection, and bioanalysis

H Dong, J Lei, L Ding, Y Wen, H Ju, X Zhang - Chemical reviews, 2013 - ACS Publications
Mature microRNAs (miRNAs) are a class of evolutionally conserved, single-stranded, small
(approximately 19− 23 nucleotides), endogenously expressed, and non-protein-coding …

MicroRNA replacement therapy in cancer

H Mollaei, R Safaralizadeh… - Journal of cellular …, 2019 - Wiley Online Library
Despite the recent progress in cancer management approaches, the mortality rate of cancer
is still growing and there are lots of challenges in the clinics in terms of novel therapeutics …

Detection, characterization and quantification of inorganic engineered nanomaterials: A review of techniques and methodological approaches for the analysis of …

F Laborda, E Bolea, G Cepriá, MT Gómez… - Analytica chimica …, 2016 - Elsevier
The increasing demand of analytical information related to inorganic engineered
nanomaterials requires the adaptation of existing techniques and methods, or the …

Nano-based delivery of RNAi in cancer therapy

Y Xin, M Huang, WW Guo, Q Huang, L Zhang, G Jiang - Molecular cancer, 2017 - Springer
Background RNA interference (RNAi), a newly developed method in which RNA molecules
inhibit gene expression, has recently received considerable research attention. In the …

Progress in microRNA delivery

Y Zhang, Z Wang, RA Gemeinhart - Journal of controlled release, 2013 - Elsevier
MicroRNAs (miRNAs) are non-coding endogenous RNAs that direct post-transcriptional
regulation of gene expression by several mechanisms. Activity is primarily through binding …

Signal amplification in living cells: a review of microRNA detection and imaging

H Peng, AM Newbigging, MS Reid, JS Uppal… - Analytical …, 2019 - ACS Publications
MicroRNA (miRNA) is a class of endogenous, noncoding RNA with a typical length of 19−
23 nucleotides (nt). 1− 3 miRNA regulate the expression of specific genes by binding to …

miRNA-guided imaging and photodynamic therapy treatment of cancer cells using Zn (II)-protoporphyrin IX-loaded metal–organic framework nanoparticles

P Zhang, Y Ouyang, YS Sohn, M Fadeev, O Karmi… - ACS …, 2022 - ACS Publications
An analytical platform for the selective miRNA-21-guided imaging of breast cancer cells and
miRNA-221-guided imaging of ovarian cancer cells and the selective photodynamic therapy …

Uptake of engineered gold nanoparticles into mammalian cells

LA Dykman, NG Khlebtsov - Chemical reviews, 2014 - ACS Publications
In the past decade, mammalian cells have increasingly encountered gold nanoparticles
(GNPs), owing to the active development of nanomedicine. 1− 3 GNPs have been more and …