The formyl peptide receptors (FPRs) are G protein-coupled receptors that transduce
chemotactic signals in phagocytes and mediate host-defense as well as inflammatory …

Formyl peptide receptors (FPRs) are a small group of seven-transmembrane domain, G
protein-coupled receptors that are expressed mainly by mammalian phagocytic leukocytes …

Formyl-peptide receptors (FPRs) recognize bacterial and mitochondrial formylated peptides
as well as endogenous non-formylated peptides and even lipids. FPRs are expressed on …

Chemokines regulate inflammation, leukocyte trafficking, and immune cell differentiation.
The role of chemokines in homing of naive T lymphocytes to secondary lymphatic organs is …

The formyl peptide receptor (FPR) family is involved in host defence against pathogens, but
also in sensing internal molecules that may constitute signals of cellular dysfunction. It …

The resolution of the inflammatory response is highly regulated by the timely biosynthesis of
a number of endogenous lipid mediators. Among these, lipoxins (LX) and their 15-epimers …

The formyl peptide receptor 2 (FPR2) is a remarkably versatile transmembrane protein
belonging to the G-protein coupled receptor (GPCR) family. FPR2 is activated by an array of …

The antimicrobial peptide LL-37 is the only cathelicidin that has been described in humans.
LL-37 exerts chemotactic, immunomodulatory and angiogenic effects; activities that are …

Amyloid ß (Aß) is a major contributor to the pathogenesis of Alzheimer's disease (AD).
Although Aß has been reported to be directly neurotoxic, it also causes indirect neuronal …

Endogenous chemical mediators or autacoids play key roles in controlling inflammation and
its programmed resolution. Among them, it is known that lipoxins (LX) and aspirin-triggered …