Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts

P Patra, M Das, P Kundu, A Ghosh - Biotechnology Advances, 2021 - Elsevier
Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …

The effects of temperature on aerobic metabolism: towards a mechanistic understanding of the responses of ectotherms to a changing environment

PM Schulte - The Journal of experimental biology, 2015 - journals.biologists.com
Because of its profound effects on the rates of biological processes such as aerobic
metabolism, environmental temperature plays an important role in shaping the distribution …

Procedures for large-scale metabolic profiling of serum and plasma using gas chromatography and liquid chromatography coupled to mass spectrometry

WB Dunn, D Broadhurst, P Begley, E Zelena… - Nature protocols, 2011 - nature.com
Metabolism has an essential role in biological systems. Identification and quantitation of the
compounds in the metabolome is defined as metabolic profiling, and it is applied to define …

[HTML][HTML] Alternative strategies for microbial remediation of pollutants via synthetic biology

S Jaiswal, P Shukla - Frontiers in microbiology, 2020 - frontiersin.org
Continuous contamination of the environment with xenobiotics and related recalcitrant
compounds has emerged as a serious pollution threat. Bioremediation is the key to …

Interactions between metal oxides and biomolecules: from fundamental understanding to applications

MJ Limo, A Sola-Rabada, E Boix, V Thota… - Chemical …, 2018 - ACS Publications
Metallo-oxide (MO)-based bioinorganic nanocomposites promise unique structures,
physicochemical properties, and novel biochemical functionalities, and within the past …

Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy

WB Dunn, DI Broadhurst, HJ Atherton… - Chemical society …, 2011 - pubs.rsc.org
The study of biological systems in a holistic manner (systems biology) is increasingly being
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …

Systems biology primer: the basic methods and approaches

I Tavassoly, J Goldfarb, R Iyengar - Essays in biochemistry, 2018 - portlandpress.com
Systems biology is an integrative discipline connecting the molecular components within a
single biological scale and also among different scales (eg cells, tissues and organ systems) …

[HTML][HTML] Yeast two-hybrid, a powerful tool for systems biology

A Brückner, C Polge, N Lentze, D Auerbach… - International journal of …, 2009 - mdpi.com
A key property of complex biological systems is the presence of interaction networks formed
by its different components, primarily proteins. These are crucial for all levels of cellular …

[HTML][HTML] Kinetic models in industrial biotechnology–improving cell factory performance

J Almquist, M Cvijovic, V Hatzimanikatis, J Nielsen… - Metabolic …, 2014 - Elsevier
An increasing number of industrial bioprocesses capitalize on living cells by using them as
cell factories that convert sugars into chemicals. These processes range from the production …

[图书][B] The logic of chance: the nature and origin of biological evolution

EV Koonin - 2011 - books.google.com
The Logic of Chance offers a reappraisal and a new synthesis of theories, concepts, and
hypotheses on the key aspects of the evolution of life on earth in light of comparative …