Stress-induced analgesia

RK Butler, DP Finn - Progress in neurobiology, 2009 - Elsevier
For over 30 years, scientists have been investigating the phenomenon of pain suppression
upon exposure to unconditioned or conditioned stressful stimuli, commonly known as stress …

Stress-induced visceral pain: toward animal models of irritable-bowel syndrome and associated comorbidities

RD Moloney, SM O'Mahony, TG Dinan… - Frontiers in …, 2015 - frontiersin.org
Visceral pain is a global term used to describe pain originating from the internal organs,
which is distinct from somatic pain. It is a hallmark of functional gastrointestinal disorders …

Repeated exposure to water avoidance stress in rats: a new model for sustained visceral hyperalgesia

S Bradesi, I Schwetz, HS Ennes… - American Journal …, 2005 - journals.physiology.org
Chronic stress plays an important role in the development and exacerbation of symptoms in
functional gastrointestinal disorders. To better understand the mechanisms underlying this …

Stress and visceral pain: from animal models to clinical therapies

M Larauche, A Mulak, Y Taché - Experimental neurology, 2012 - Elsevier
Epidemiological studies have implicated stress (psychosocial and physical) as a trigger of
first onset or exacerbation of irritable bowel syndrome (IBS) symptoms of which visceral pain …

The role of neurotensin in central nervous system pathophysiology: what is the evidence?

F St-Gelais, C Jomphe, LÉ Trudeau - Journal of Psychiatry and …, 2006 - jpn.ca
The peptide neurotensin has been studied for more than 30 years. Although it is widely
distributed in the central and peripheral nervous systems, neurotensin has been more …

Diverse roles of neurotensin agonists in the central nervous system

M Boules, Z Li, K Smith, P Fredrickson… - Frontiers in …, 2013 - frontiersin.org
Neurotensin (NT) is a tridecapeptide that is found in the central nervous system (CNS) and
the gastrointestinal tract. NT behaves as a neurotransmitter in the brain and as a hormone in …

The role of neurotensin in physiologic and pathologic processes

WC Mustain, PG Rychahou… - Current Opinion in …, 2011 - journals.lww.com
The review highlights the wide array of biological processes in which neurotensin has a role,
and summarizes the most recent advances in various fields of neurotensin research. The …

Changes in biochemical markers of pain perception and stress response after spinal manipulation

G Plaza-Manzano, F Molina, R Lomas-Vega… - journal of orthopaedic & …, 2014 - jospt.org
Study Design Controlled, repeated-measures, single-blind randomized study. Objectives To
determine the effect of cervical or thoracic manipulation on neurotensin, oxytocin, orexin A …

Neurotensin and neurotensin receptors: Characteristic, structure–activity relationship and pain modulation—A review

P Kleczkowska, AW Lipkowski - European journal of pharmacology, 2013 - Elsevier
Neurotensin (NT) is a tridecapeptide, which–since its discovery in 1973–has been
demonstrated to be involved in the control of various physiological activities in both the …

Neurotensin and pain modulation

PR Dobner - Peptides, 2006 - Elsevier
Neurotensin (NT) can produce a profound analgesia or enhance pain responses,
depending on the circumstances. Recent evidence suggests that this may be due to a dose …