Pentagamavunone-1 inhibits aggressive breast cancer cell proliferation through mitotic catastrophe and ROS-mediated activities: in vitro and in vivo studies
D Novitasari, I Nakamae, RI Jenie… - Saudi Pharmaceutical …, 2024 - Elsevier
Abstract Pentagamavunone-1 (PGV-1), an analog of curcumin, has been studied for its
cytotoxic effects in 4T1, MCF7, MCF7/HER2, and T47D breast cancer cells. Its …
cytotoxic effects in 4T1, MCF7, MCF7/HER2, and T47D breast cancer cells. Its …
[HTML][HTML] Different Modes of Mechanism of Gamma-Mangostin and Alpha-Mangostin to Inhibit Cell Migration of Triple-Negative Breast Cancer Cells Concerning …
S Sarmoko, D Novitasari, M Toriyama… - Iranian Journal of …, 2023 - ncbi.nlm.nih.gov
Background Two mangostin compounds, gamma-mangostin and alpha-mangostin, show
anticancer properties through the inhibition of cell proliferation and cell migration. Metastatic …
anticancer properties through the inhibition of cell proliferation and cell migration. Metastatic …
[HTML][HTML] PGV-1 Causes Disarrangement of Spindle Microtubule Organization Resulting in Aberrant Mitosis in HLF and HuH6 Cells Associated with Altered MYCN …
N Nugraheni, UM Zulfin, B Lestari… - Advanced …, 2024 - pmc.ncbi.nlm.nih.gov
Purpose: The HLF and HuH-6 cell lines represent hepatocellular carcinoma (HCC) with
different characteristics in chromosome content that may give different drug responses …
different characteristics in chromosome content that may give different drug responses …
Diosmin Enhances the Anti-migration Activity of Curcumin Analog PGV-1 on Colorectal Cancer Cells
BACKGROUND: Diosmin enhances the cytotoxicity of Pentagamavunone-1 (PGV-1) in
cancer cells. PGV-1 and diosmin are predicted to target several matrix metalloproteinases …
cancer cells. PGV-1 and diosmin are predicted to target several matrix metalloproteinases …
Chromolaena odorata L. Leaf Extract Elevates Cytotoxicity of Doxorubicin on 4T1 Breast Cancer Cells
AP Putri, DR Rahmawati, FA Rahman… - … Journal of Cancer …, 2023 - ijcc.chemoprev.org
Chemotherapeutic agents for breast cancer such as doxorubicin can attack normal cells as
the side effects. Chromolaena odorata L. and its chemical content, sinensetin, have potential …
the side effects. Chromolaena odorata L. and its chemical content, sinensetin, have potential …