Atherosclerosis is a chronic inflammatory vascular disease and the predominant cause of
heart attack and ischemic stroke. Despite the well-known sexual dimorphism in the …

Although once primarily recognized for its roles in hemostasis and thrombosis, the platelet
has been increasingly recognized as a multipurpose cell. Indeed, circulating platelets have …

Clinical observations implicate a role of eosinophils in cardiovascular diseases because
markers of eosinophil activation are elevated in atherosclerosis and thrombosis. However …

Platelets, besides their specialised role in haemostasis and atherothrombosis, actively
modulate innate and adaptive immune responses with crucial roles in immune surveillance …

Besides their role in hemostasis and thrombosis, it has become increasingly clear that
platelets are also involved in many other pathological processes of the vascular system …

In patients with sickle cell disease (SCD), the polymerization of intraerythrocytic hemoglobin
S promotes downstream vaso-occlusive events in the microvasculature. While vaso …

The role of platelet adhesion, activation, and aggregation in acute atherothrombotic events
such as myocardial infarction and stroke is well established. There is increasing evidence …

Platelets are important actors of cardiovascular diseases (CVD). Current antiplatelet drugs
that inhibit platelet aggregation have been shown to be effective in CVD treatment. However …

Background: Platelet-neutrophil interactions contribute to vascular occlusion and tissue
damage in thromboinflammatory disease. Platelet glycoprotein Ibα (GPIbα), a key receptor …

Platelets and platelet-derived microparticles (PMPs) play important roles in cardiovascular
diseases, especially atherosclerosis. Continued research has revealed that PMPs have …