Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts
Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …
sources is currently an advancing area in industrial research. The model yeast …
Engineering strategies for enhanced production of protein and bio-products in Pichia pastoris: a review
Z Yang, Z Zhang - Biotechnology advances, 2018 - Elsevier
Pichia pastoris has been recognized as one of the most industrially important hosts for
heterologous protein production. Despite its high protein productivity, the optimization of P …
heterologous protein production. Despite its high protein productivity, the optimization of P …
Methanol biotransformation toward high-level production of fatty acid derivatives by engineering the industrial yeast Pichia pastoris
P Cai, X Wu, J Deng, L Gao, Y Shen… - Proceedings of the …, 2022 - National Acad Sciences
Methanol-based biorefinery is a promising strategy to achieve carbon neutrality goals by
linking CO2 capture and solar energy storage. As a typical methylotroph, Pichia pastoris …
linking CO2 capture and solar energy storage. As a typical methylotroph, Pichia pastoris …
Systems metabolic engineering strategies: integrating systems and synthetic biology with metabolic engineering
Metabolic engineering allows development of microbial strains efficiently producing
chemicals and materials, but it requires much time, effort, and cost to make the strains …
chemicals and materials, but it requires much time, effort, and cost to make the strains …
Biocatalyst for the synthesis of natural flavouring compounds as food additives: Bridging the gap for a more sustainable industrial future
S Singh, PK Sharma, S Chaturvedi, P Kumar… - Food Chemistry, 2024 - Elsevier
Biocatalysis entails the use of purified enzymes in the manufacturing of flavouring chemicals
food industry as well as at the laboratory level. These biocatalysts can significantly …
food industry as well as at the laboratory level. These biocatalysts can significantly …
[HTML][HTML] Metabolic engineering of Pichia pastoris
Besides its use for efficient production of recombinant proteins the methylotrophic yeast
Pichia pastoris (syn. Komagataella spp.) has been increasingly employed as a platform to …
Pichia pastoris (syn. Komagataella spp.) has been increasingly employed as a platform to …
Industrial Production of Proteins with Pichia pastoris—Komagataella phaffii
GD Barone, A Emmerstorfer-Augustin, A Biundo… - Biomolecules, 2023 - mdpi.com
Since the mid-1960s, methylotrophic yeast Komagataella phaffii (previously described as
Pichia pastoris) has received increasing scientific attention. The interest for the industrial …
Pichia pastoris) has received increasing scientific attention. The interest for the industrial …
Heterologous Protein Expression in Pichia pastoris: Latest Research Progress and Applications
V Juturu, JC Wu - ChemBioChem, 2018 - Wiley Online Library
Pichia pastoris is a well‐known platform strain for heterologous protein expression. Over the
past five years, different strategies to improve the efficiency of recombinant protein …
past five years, different strategies to improve the efficiency of recombinant protein …
Biosynthesis of catharanthine in engineered Pichia pastoris
J Gao, Y Zuo, F Xiao, Y Wang, D Li, J Xu, C Ye… - Nature …, 2023 - nature.com
Catharanthine can be coupled with vindoline to synthesize vinblastine and vincristine, which
have been used clinically as potent anticancer drugs. However, the structural complexity …
have been used clinically as potent anticancer drugs. However, the structural complexity …
Barriers and opportunities in bio-based production of hydrocarbons
Global climate change caused by the accumulation of greenhouse gases (GHGs) has
caused concerns regarding the continued reliance on fossil fuels as our primary energy …
caused concerns regarding the continued reliance on fossil fuels as our primary energy …