Replacement of the furanosyl oxygen with a methylene unit in the ribose sugar in
nucleosides 1 and nucleotides 2 prompted the rise of a new nucleoside class with very …

The recent advances in the chemistry of carbocyclic nucleosides focused on different
synthetic approaches that lead to optically pure products as well as a comprehensive …

Adenosine receptor agonists have cardioprotective, cerebroprotective, and antiinflammatory
properties. We report that a carbocyclic modification of the ribose moiety incorporating ring …

Two isomers of methanocarba (MC) thymidine (T), one an effective antiherpes agent with the
pseudosugar moiety locked in the North (N) hemisphere of the pseudorotational cycle (1a, N …

A new total synthesis of the antitumor alkaloids, pancratistatin (1), has been accomplished
from readily available staring materials. The Claisen rearrangement of …

Reported herein is the iridium‐catalyzed regio‐and enantioselective allylic substitution
reactions of unstabilized silyl dienolates derived from dioxinones. Asymmetric allylic …

A mild photoredox-catalyzed intramolecular cyclopropanation of alkenes with α-bromo-β-
keto esters in an aqueous medium was developed. The sequential reaction process …

A new total synthesis of the antitumor alkaloid, pancratistatin (1), has been accomplished
from readily available starting materials. Claisen rearrangement of the racemic …

Isoxazole, isoxazoline and isoxazolidine analogues of C-nucleosides related to
pseudouridine have been synthesized by 1, 3-dipolar cycloaddition reactions of nitrile …

Nucleoside derivatives are well represented as pharmaceuticals due to their druglike
physicochemical properties, and some nucleoside drugs are designed to act on receptors …