Advances in growth factor delivery for bone tissue engineering

ÉR Oliveira, L Nie, D Podstawczyk… - International journal of …, 2021 - mdpi.com
Shortcomings related to the treatment of bone diseases and consequent tissue regeneration
such as transplants have been addressed to some extent by tissue engineering and …

Electrospinning for regenerative medicine: a review of the main topics

DI Braghirolli, D Steffens, P Pranke - Drug discovery today, 2014 - Elsevier
Highlights•Electrospun scaffolds physically mimic the native extracellular matrix.•Techniques
for physicochemical and biological characterization of scaffolds are discussed.•MSCs have …

Chitosan wound dressings incorporating exosomes derived from microRNA-126-overexpressing synovium mesenchymal stem cells provide sustained release of …

SC Tao, SC Guo, M Li, QF Ke, YP Guo… - Stem cells …, 2017 - academic.oup.com
There is a need to find better strategies to promote wound healing, especially of chronic
wounds, which remain a challenge. We found that synovium mesenchymal stem cells …

Tailored design of electrospun composite nanofibers with staged release of multiple angiogenic growth factors for chronic wound healing

HJ Lai, CH Kuan, HC Wu, JC Tsai, TM Chen, DJ Hsieh… - Acta biomaterialia, 2014 - Elsevier
The objective of this research study is to develop a collagen (Col) and hyaluronic acid (HA)
inter-stacking nanofibrous skin equivalent substitute with the programmable release of …

Blood‐lymphatic integrated system with heterogeneous melanoma spheroids via in‐bath three‐dimensional bioprinting for modelling of combinational targeted …

WW Cho, M Ahn, BS Kim, DW Cho - Advanced Science, 2022 - Wiley Online Library
Although metastatic melanoma can be managed with chemotherapy, its heterogeneity and
resistance to therapy remain poorly understood. In addition to the spread of melanoma in the …

Electrospun nanofibers for improved angiogenesis: promises for tissue engineering applications

S Nazarnezhad, F Baino, HW Kim, TJ Webster… - Nanomaterials, 2020 - mdpi.com
Angiogenesis (or the development of new blood vessels) is a key event in tissue
engineering and regenerative medicine; thus, a number of biomaterials have been …

Secured delivery of basic fibroblast growth factor using human serum albumin-based protein nanoparticles for enhanced wound healing and regeneration

B Son, M Kim, H Won, A Jung, J Kim, Y Koo… - Journal of …, 2023 - Springer
Background Basic fibroblast growth factor (bFGF) is one of the critical components
accelerating angiogenesis and tissue regeneration by promoting the migration of dermal …

Antifibrotic therapies to control cardiac fibrosis

Z Fan, J Guan - Biomaterials research, 2016 - spj.science.org
Cardiac fibrosis occurs naturally after myocardial infarction. While the initially formed fibrotic
tissue prevents the infarcted heart tissue from rupture, the progression of cardiac fibrosis …

[HTML][HTML] Vascular restoration through local delivery of angiogenic factors stimulates bone regeneration in critical size defects

L Fang, Z Liu, C Wang, M Shi, Y He, A Lu, X Li, T Li… - Bioactive Materials, 2024 - Elsevier
Critical size bone defects represent a significant challenge worldwide, often leading to
persistent pain and physical disability that profoundly impact patients' quality of life and …

Physicochemical characterization of nanofiber composites

A Polini, F Yang - Nanofiber composites for biomedical applications, 2017 - Elsevier
Nanofiber composites have huge potential to be used for tissue engineering and
regenerative medicine. This type of material possesses at least two distinct phases and may …