Recent advances in overcoming barriers to cell‐based delivery systems for cancer immunotherapy

Y Ding, Y Wang, Q Hu - Exploration, 2022 - Wiley Online Library
Immunotherapy strategies that use cell‐based delivery systems have sparked much interest
in the treatment of malignancies, owing to their high biocompatibility, excellent tumor …

Stem cell membrane, stem cell-derived exosomes and hybrid stem cell camouflaged nanoparticles: A promising biomimetic nanoplatforms for cancer theranostics

N Khosravi, E Pishavar, B Baradaran… - Journal of Controlled …, 2022 - Elsevier
Nanomedicine research has advanced dramatically in recent decades. Nonetheless,
traditional nanomedicine faces significant obstacles such as the low concentration of the …

Genetically engineered and enucleated human mesenchymal stromal cells for the targeted delivery of therapeutics to diseased tissue

H Wang, CN Alarcón, B Liu, F Watson… - Nature biomedical …, 2022 - nature.com
Targeting the delivery of therapeutics specifically to diseased tissue enhances their efficacy
and decreases their side effects. Here we show that mesenchymal stromal cells with their …

Functional nanomaterials in biomedicine: Current uses and potential applications

AM Diez‐Pascual, A Rahdar - ChemMedChem, 2022 - Wiley Online Library
Nanomaterials, that is, materials made up of individual units between 1 and 100
nanometers, have lately involved a lot of attention since they offer a lot of potential in many …

Characteristics and clinical applications of Wharton's jelly-derived mesenchymal stromal cells

LL Liau, BHI Ruszymah, MH Ng, JX Law - Current research in translational …, 2020 - Elsevier
Mesenchymal stromal cells (MSCs) are widely used in the clinic because they involve fewer
ethical issues and safety concerns compared to other stem cells such as embryonic stem …

Surface engineering of nanomaterials with polymers, biomolecules, and small ligands for nanomedicine

AM Díez-Pascual - Materials, 2022 - mdpi.com
Nanomedicine is a speedily growing area of medical research that is focused on developing
nanomaterials for the prevention, diagnosis, and treatment of diseases. Nanomaterials with …

Current strategies in assessment of nanotoxicity: alternatives to in vivo animal testing

HJ Huang, YH Lee, YH Hsu, CT Liao, YF Lin… - International journal of …, 2021 - mdpi.com
Millions of experimental animals are widely used in the assessment of toxicological or
biological effects of manufactured nanomaterials in medical technology. However, the …

Blood–brain barrier disruption and its involvement in neurodevelopmental and neurodegenerative disorders

A Aragón-González, PJ Shaw, L Ferraiuolo - International journal of …, 2022 - mdpi.com
The blood–brain barrier (BBB) is a highly specialized and dynamic compartment which
regulates the uptake of molecules and solutes from the blood. The relevance of the …

TRAIL in the treatment of cancer: from soluble cytokine to nanosystems

H Alizadeh Zeinabad, E Szegezdi - Cancers, 2022 - mdpi.com
Simple Summary TRAIL is a death ligand cytokine, predominantly used by effector immune
cells to kill malignantly transformed cells. Since its discovery, TRAIL has attracted a lot of …

Smart polymers for cell therapy and precision medicine

HJ Huang, YL Tsai, SH Lin, S Hsu - Journal of biomedical science, 2019 - Springer
Soft materials have been developed very rapidly in the biomedical field over the past 10
years because of advances in medical devices, cell therapy, and 3D printing for precision …