Nonribosomal peptide synthetases (NRPSs) are large multienzyme machineries that
assemble numerous peptides with large structural and functional diversity. These peptides …

Sulfur plays a critical role for the development and maintenance of life on earth, which is
reflected by the wealth of primary metabolites, macromolecules, and cofactors bearing this …

Natural microbial communities are phylogenetically and metabolically diverse. In addition to
underexplored organismal groups, this diversity encompasses a rich discovery potential for …

Nonribosomal peptide synthetases (NRPSs) are incredible macromolecular machines that
produce a wide range of biologically-and therapeutically-relevant molecules. During …

Complex peptide natural products exhibit diverse biological functions and a wide range of
physico-chemical properties. As a result, many peptides have entered the clinics for various …

Nonribosomal peptides (NRP) are crucial molecular mediators in microbial ecology and
provide indispensable drugs. Nevertheless, the evolution of the flexible biosynthetic …

Microorganisms are remarkable chemists, with enzymes as their tools for executing multi-
step syntheses to yield myriad natural products. Microbial synthetic aptitudes are illustrated …

Covering: up to fall 2022. Nonribosomal peptide synthetases (NRPSs) are a family of
modular, multidomain enzymes that catalyze the biosynthesis of important peptide natural …

Covering: up to July 2018 Non-ribosomal peptide synthetase (NRPS) machineries are
complex, multi-domain proteins that are responsible for the biosynthesis of many important …

Nonribosomal peptide synthetases (NRPSs) produce a wide variety of peptide natural
products. During synthesis, the multidomain NRPSs act as an assembly line, passing the …