Updating the mitochondrial free radical theory of aging: an integrated view, key aspects, and confounding concepts
G Barja - Antioxidants & redox signaling, 2013 - liebertpub.com
An updated version of the mitochondrial free radical theory of aging (MFRTA) and longevity
is reviewed. Key aspects of the theory are emphasized. Another main focus concerns …
is reviewed. Key aspects of the theory are emphasized. Another main focus concerns …
Potential of garlic (Allium sativum) in lowering high blood pressure: mechanisms of action and clinical relevance
K Ried, P Fakler - Integrated blood pressure control, 2014 - Taylor & Francis
Garlic supplements have shown promise in the treatment of uncontrolled hypertension,
lowering blood pressure (BP) by about 10 mmHg systolic and 8 mmHg diastolic, similar to …
lowering blood pressure (BP) by about 10 mmHg systolic and 8 mmHg diastolic, similar to …
[HTML][HTML] Redox signaling (cross-talk) from and to mitochondria involves mitochondrial pores and reactive oxygen species
A Daiber - Biochimica et Biophysica Acta (BBA)-Bioenergetics, 2010 - Elsevier
This review highlights the important role of redox signaling between mitochondria and
NADPH oxidases. Besides the definition and general importance of redox signaling, the …
NADPH oxidases. Besides the definition and general importance of redox signaling, the …
Human absorption and metabolism of oleuropein and hydroxytyrosol ingested as olive (Olea europaea L.) leaf extract
M De Bock, EB Thorstensen… - Molecular nutrition & …, 2013 - Wiley Online Library
Phenolic compounds derived from the olive plant (Olea europaea L.), particularly
hydroxytyrosol and oleuropein, have many beneficial effects in vitro. Olive leaves are the …
hydroxytyrosol and oleuropein, have many beneficial effects in vitro. Olive leaves are the …
Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H2O2 and superoxide dismutase activity
A Mesquita, M Weinberger, A Silva… - Proceedings of the …, 2010 - National Acad Sciences
The free radical theory of aging posits oxidative damage to macromolecules as a primary
determinant of lifespan. Recent studies challenge this theory by demonstrating that in some …
determinant of lifespan. Recent studies challenge this theory by demonstrating that in some …
Dietary antioxidant capacity and risk of type 2 diabetes mellitus, prediabetes and insulin resistance: the Rotterdam Study
N van der Schaft, JD Schoufour, J Nano… - European journal of …, 2019 - Springer
Intake of individual antioxidants has been related to a lower risk of type 2 diabetes.
However, the overall diet may contain many antioxidants with additive or synergistic effects …
However, the overall diet may contain many antioxidants with additive or synergistic effects …
Ginger (Zingiber officinale) and chemotherapy-induced nausea and vomiting: a systematic literature review
Chemotherapy-induced nausea and vomiting (CINV) is a common side-effect of cytotoxic
treatment. It continues to affect a significant proportion of patients despite the widespread …
treatment. It continues to affect a significant proportion of patients despite the widespread …
Drug development for the therapy of mitochondrial diseases
V Weissig - Trends in molecular medicine, 2020 - cell.com
Mitochondrial diseases are a heterogeneous group of inherited or acquired devastating
disorders that affect the energy metabolism of the body. Many strategies have been …
disorders that affect the energy metabolism of the body. Many strategies have been …
The role of iron in mitochondrial function
S Levi, E Rovida - Biochimica et Biophysica Acta (BBA)-General Subjects, 2009 - Elsevier
BACKGROUND: Iron is an essential element for life, as it is a cofactor for enzymes involved
in many metabolic processes, but it can also be harmful, since its excess is thought to …
in many metabolic processes, but it can also be harmful, since its excess is thought to …
Ginger—Mechanism of action in chemotherapy-induced nausea and vomiting: A review
Despite advances in antiemetic therapy, chemotherapy-induced nausea and vomiting
(CINV) still poses a significant burden to patients undergoing chemotherapy. Nausea, in …
(CINV) still poses a significant burden to patients undergoing chemotherapy. Nausea, in …