Varicocoele‐associated male infertility: Cellular and molecular perspectives of pathophysiology

D Arya, N Balasinor, D Singh - Andrology, 2022 - Wiley Online Library
Background Varicocoele is a common risk factor associated with reduced male fertility
potential. The current understanding of varicocoele pathophysiology does not completely …

[HTML][HTML] Oxidative stress: a comprehensive review of biochemical, molecular, and genetic aspects in the pathogenesis and management of varicocele

R Finelli, K Leisegang, H Kandil… - The World Journal of …, 2022 - ncbi.nlm.nih.gov
Oxidative stress is a condition due to an imbalance between the concentrations of oxidants
and antioxidants, and it is a well-recognized contributor in several male infertility conditions …

[HTML][HTML] Comprehensive analysis of global research on human varicocele: a scientometric approach

A Agarwal, R Finelli, D Durairajanayagam… - The World Journal of …, 2022 - ncbi.nlm.nih.gov
Purpose This study provides a comprehensive analysis of research trends on the etiology,
mechanisms, potential risk factors, diagnosis, prognosis, surgical and non-surgical treatment …

Resveratrol benefits on sperm DNA, chromatin structure and reproductive outcomes of varicocelized rats

TB Mendes, JN Simas, LW Fischer, CC Paccola… - Andrologia, 2022 - Wiley Online Library
In varicocele, the main cause of sperm DNA damage is oxidative stress (OS). Resveratrol, a
polyphenol with antioxidant properties, can protect cells from injuries caused by OS. We …

[HTML][HTML] Molecular characteristics of varicocele: integration of whole-exome and transcriptome sequencing

B Yang, Y Yang, Y Liu, H Li, S Ren, Z Peng, K Fang… - Fertility and sterility, 2021 - Elsevier
Objective To explore the exome and transcriptome characteristics potentially underlying the
pathogenesis of varicocele (VE). Design Experimental study and cohort study. Setting …

Genetic variants in varicocele-related male infertility: a systematic review and future directions

T Mostafa, I Abdel-Hamid, M Taymour, O Ali - Human Fertility, 2023 - Taylor & Francis
Genetic association studies (GAS) may have the capability to probe the genetic susceptibility
alleles in many disorders. This systemic review aimed to assess whether an association …

[HTML][HTML] The association between TNP2 gene polymorphisms and Iranian infertile men with varicocele: A case-control study

MM Heidari, A Danafar, F Moezzi… - International Journal …, 2019 - ncbi.nlm.nih.gov
Background Numerous researches have provided great evidence that revealed the
relationship between varicocele and sperm DNA damage. Objective Because of the crucial …

[PDF][PDF] Therapy in Oligozoospermia (Varicocele, Cryptorchidism, Inflammation, and Seminal Tract Infections)

GM Busetto, R Saleh, M Gül… - Practical Clinical …, 2022 - library.oapen.org
Varicocele is an abnormal dilatation, elongation, and tortuosity of the pampiniform plexus of
veins draining the testicles and is associated with venous reflux. Varicocele is diagnosed on …

Identification of the PRM1 gene mutations in oligoasthenoteratozoospermic men

M Nasirshalal, M Tahmasebi‐Birgani, M Dadfar… - Andrologia, 2020 - Wiley Online Library
Mutations or altered expression of PRM1 gene have been associated with male infertility.
This study aimed to analyse pathogenic variations of PRM1 gene in Iranian Arab infertile …

Semen Parameters Can be Used as a Credible Marker with Doppler Ultrasonography in the Diagnosis of Subclinical Varicocele Cases

T Irez, B Sarikaya, M Erguven, E Salabas - Gynecology Obstetrics & …, 2024 - gorm.com.tr
OBJECTIVES: The link between varicoceles and male infertility has been a problem of
debate for more than half a century. A substantial amount of data about varicocelectomies' …