Angiotropism, pericytic mimicry and extravascular migratory metastasis: an embryogenesis-derived program of tumor spread

C Lugassy, HK Kleinman, PB Vermeulen, RL Barnhill - Angiogenesis, 2020 - Springer
Intravascular dissemination of tumor cells is the accepted mechanism of cancer metastasis.
However, the phenomenon of angiotropism, pericyte mimicry (PM), and extravascular …

[HTML][HTML] Role of miRNA in the regulation of blood group expression

R Kronstein-Wiedemann, SR Künzel, J Thiel… - Transfusion Medicine …, 2024 - karger.com
Background: MicroRNAs (miRNAs) are small, endogenous non-coding RNA molecules that
inhibit gene expression through either destabilization of the target mRNA or translational …

Photoproximity Labeling from Single Catalyst Sites Allows Calibration and Increased Resolution for Carbene Labeling of Protein Partners In Vitro and on Cells

TG Bartholow, PWW Burroughs, SK Elledge… - ACS Central …, 2023 - ACS Publications
The cell surface proteome (surfaceome) plays a pivotal role in virtually all extracellular
biology, and yet we are only beginning to understand the protein complexes formed in this …

BCAM Deficiency may contribute to preeclampsia by suppressing the PIK3R6/p-STAT3 signaling

M Liu, L Liao, Y Gao, Y Yin, X Wei, Q Xu, L Gao… - …, 2022 - Am Heart Assoc
Background: Preeclampsia is a pregnancy syndrome that may utilize multiple pathogenic
mechanisms. Insufficient trophoblast invasion and impaired uterine spiral artery remodeling …

Type 2 inflammation drives an airway basal stem cell program through insulin receptor substrate signaling

X Wang, NR Hallen, M Lee, S Samuchiwal, Q Ye… - Journal of Allergy and …, 2023 - Elsevier
Background Chronic rhinosinusitis with nasal polyposis (CRSwNP) is a type 2 (T2)
inflammatory disease associated with an increased number of airway basal cells (BCs) …

Basal cell adhesion molecule promotes metastasis‐associated processes in ovarian cancer

S Sivakumar, S Lieber, D Librizzi… - Clinical and …, 2023 - Wiley Online Library
Background Basal cell adhesion molecule (BCAM) is a laminin α5 (LAMA5) binding
membrane‐bound protein with a putative role in cancer. Besides full‐length BCAM1, an …

Circular RNA-related CeRNA network and prognostic signature for patients with oral squamous cell carcinoma

Y He, D Yang, Y Li, J Xiang, L Wang… - Frontiers in …, 2022 - frontiersin.org
Background: Circular RNA (circRNA) has an important influence on oral squamous cell
carcinoma (OSCC) progression as competing endogenous RNAs (ceRNAs). However, the …

Laminins regulate placentation and pre-eclampsia: focus on trophoblasts and endothelial cells

M Liu, Y Yin, H Yu, R Zhou - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
Pre-eclampsia is a systemic vascular disease characterized by new-onset hypertension
and/or proteinuria at≥ 20 weeks of gestation and leads to high rates of maternal and …

The underlying molecular mechanism and potential drugs for treatment in papillary renal cell carcinoma: a study based on TCGA and Cmap datasets

JS Pang, ZK Li, P Lin, XD Wang… - Oncology …, 2019 - spandidos-publications.com
Papillary renal cell carcinoma (PRCC) accounts for 15‑20% of all kidney neoplasms and
continually attracts attention due to the increase in the incidents in which it occurs. The …

Site-specific proximity labeling at single residue resolution for identification of protein partners in vitro and on cells

TG Bartholow, P Burroughs, SK Elledge, JR Byrnes… - bioRxiv, 2023 - biorxiv.org
The cell surface proteome, or surfaceome, is encoded by more than 4000 genes, but we are
only beginning to understand the complexes they form. Rapid proximity labeling around …