[HTML][HTML] Oxidative stress, epigenetic regulation and pathological processes of lens epithelial cells underlying diabetic cataract

Z Guo, X Ma, RX Zhang, H Yan - Advances in ophthalmology practice and …, 2023 - Elsevier
Background Cataract is a blinding disease worldwide. It is an age-related disease that
mainly occurs in people over 65 years old. Cataract is also prevalent in patients with …

Enzymatic and biochemical properties of lens in age-related cataract versus diabetic cataract: A narrative review

D Mishra, A Kashyap, T Srivastav… - Indian Journal of …, 2023 - journals.lww.com
Cataract is the leading cause of blindness worldwide. There is an increased incidence of
cataract formation in the diabetic population due to several factors. Diabetes mellitus …

FUNDC1 induces apoptosis and autophagy under oxidative stress via PI3K/Akt/mTOR pathway in cataract lens cells

D Dong, J Wu, L Sheng, X Gong, Z Zhang… - Current Eye …, 2022 - Taylor & Francis
Purpose The purpose of the study is to explore the mRNA and protein expression of
FUNDC1 in cataract cells and tissues, and clarify the function and mechanism of FUNDC1 in …

[HTML][HTML] Analysis of N6-methyladenosine-modified mRNAs in diabetic cataract

L Cai, XY Han, D Li, DM Ma, YM Shi, Y Lu… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Cataracts remain a prime reason for visual disturbance and blindness all
over the world, despite the capacity for successful surgical replacement with artificial lenses …

Association of Glutathione Peroxidase 3 (GPx3) and miR-196a with Carbohydrate Metabolism Disorders in the Elderly

A Włodarski, I Szymczak-Pajor, J Kasznicki… - International Journal of …, 2024 - mdpi.com
The escalating prevalence of carbohydrate metabolism disorders (CMDs) prompts the need
for early diagnosis and effective markers for their prediction. Hyperglycemia, the primary …

Associations of exposure to multiple metals with the risk of age-related cataract in Anhui, China: a case–control study

YQ Li, Q Wang, R Liu, GA Li, JL He, F Huang… - … Science and Pollution …, 2023 - Springer
It's well-known that multiple metal elements can lead to the change of oxidative stress
response levels in vivo. However, their relationship with age-related cataract (ARC) had not …

Serum magnesium levels in patients with obstructive sleep apnoea: a systematic review and meta-analysis

Z Al Wadee, SL Ooi, SC Pak - Biomedicines, 2022 - mdpi.com
Aims: Obstructive sleep apnoea (OSA) affects patients' quality of life and health. Magnesium
(Mg) is an essential mineral and a potent antioxidant. Mg deficiency can worsen oxidative …

[HTML][HTML] Astragalin attenuates diabetic cataracts via inhibiting aldose reductase activity in rats

N Wang, D Singh, Q Wu - International Journal of Ophthalmology, 2023 - ncbi.nlm.nih.gov
AIM To investigate the aldose reductase (AR) inhibition capacity of astragalin (AST) against
streptozoticin-induced diabetic cataracts (DCs) in rats. METHODS Ex vivo investigations …

MDM2-mediated ubiquitination of LKB1 contributes to the development of diabetic cataract

X Li, X Sun, L Li, Y Luo, Y Chi, G Zheng - Experimental Cell Research, 2022 - Elsevier
Diabetic cataract (DC) is a common complication of diabetes mellitus. The epithelial-
mesenchymal transition (EMT) of lens epithelial cells (LECs) is a crucial event in the …

The role and mechanism of various trace elements in atherosclerosis

T Zeng, GL Lei, ML Yu, TY Zhang, ZB Wang… - International …, 2024 - Elsevier
Atherosclerosis is a slow and complex disease that involves various factors, including lipid
metabolism disorders, oxygen-free radical production, inflammatory cell infiltration, platelet …