Obesity has tripled over the past 40 years to become a major public health issue, as it is
linked with increased mortality and elevated risk for various physical and neuropsychiatric …

ADHD is a disorder characterized by changes in the reward system and which is highly
comorbid with other mental disorders, suggesting common neurobiological pathways …

Theoretical work suggests that obesity is related to enhanced incentive salience of food
cues. However, evidence from both behavioral and neuroimaging studies on the topic is …

Forming and comparing subjective values (SVs) of choice options is a critical stage of
decision-making. Previous studies have highlighted a complex network of brain regions …

Abstract Purpose of Review Hyper-palatable foods (HPF) may exploit our neurobiological
propensities to seek and consume rewarding foods. The review highlights evidence from …

Variations in body mass index (BMI) have been suggested to relate to atypical brain
organization, yet connectome-level substrates of BMI and their neurobiological …

Purpose Pediatric obesity is a growing public health concern. Previous work has observed
diet to impact nucleus accumbens (NAcc) inflammation in rodents, measured by the reactive …

Cigarette smoking and obesity are the leading causes of premature morbidity and mortality
and increase the risk of all-cause mortality four-fold when comorbid. Individuals with these …

Dysregulated neural mechanisms in reward and somatosensory circuits result in an
increased appetitive drive for and reduced inhibitory control of eating, which in turn causes …

Prediction errors (PEs) encode the difference between expected and actual action outcomes
in the brain via dopaminergic modulation. Integration of these learning signals ensures …