Ultrasonic neuromodulation is a rapidly growing field, in which low-intensity ultrasound (US)
is delivered to nervous system tissue, resulting in transient modulation of neural activity. This …

Background There is an emerging need for noninvasive neuromodulation techniques to
improve patient outcomes while minimizing adverse events and morbidity. Low-intensity …

Transcranial focused ultrasound (FUS) is making progress as a new non-invasive mode of
regional brain stimulation. Current evidence of FUS-mediated neurostimulation for humans …

Background Recent advances have enabled delivery of high-intensity focused ultrasound
through the intact human cranium with magnetic resonance imaging (MRI) guidance. This …

Focused ultrasound (FUS) has recently been investigated as a new mode of non-invasive
brain stimulation, which offers exquisite spatial resolution and depth control. We report on …

Diagnostic ultrasound has been clinically used for decades. More recently, high intensity
focused ultrasound (HIFU) has been developed for therapeutic use as a non-invasive …

Electromagnetic-based methods of stimulating brain activity require invasive procedures or
have other limitations. Deep-brain stimulation requires surgically implanted electrodes …

There are several different surgical procedures that are used to treat essential tremor (ET),
including deep brain stimulation (DBS) and thalamotomy procedures with radiofrequency …

The blood–brain barrier (BBB) prevents entry of most drugs into the brain and is a major
hurdle to the use of drugs for brain tumors and other central nervous system disorders. Work …

The characterization and calibration of ultrasound imaging systems requires tissue-
mimicking phantoms with known acoustic properties, dimensions and internal features …