The blood-brain barrier (BBB) is a dynamic interface between the peripheral blood supply
and the cerebral parenchyma, controlling the transport of material to and from the brain …

Blood–brain barrier pathology is recognised as a central factor in the development of many
neurological disorders, but much less is known about the role of the blood–brain barrier in …

Using behavioral, pharmacological, and molecular methods, lots of studies reveal that
depression is closely related to the abnormal neural plasticity processes occurring in the …

Background Brain-derived neurotrophic factor (BDNF) is a neurotrophin involved in
neurogenesis and synaptic plasticity in the central nervous system, especially in the …

Executive dysfunction is increasingly recognized as one of the widely observed dimensions
of cognitive impairments in the course of schizophrenia (SCZ). However, the potential …

Background Schizophrenia is associated with patterns of aberrant neurobiological circuitry.
The disease complexity is mirrored by multiple biological interactions known to contribute to …

Recent findings implicate alterations in glutamate signaling, leading to aberrant synaptic
plasticity, in schizophrenia. Matrix metalloproteinase-9 (MMP-9) has been shown to regulate …

The study of gene× environment, as well as epistatic interactions in schizophrenia, has
provided important insight into the complex etiopathologic basis of schizophrenia. It has also …

Objectives: Brain-derived neurotrophic factor (BDNF) is involved in numerous cognitive
processes. Since cognitive deficits are a core feature of psychotic disorders, the …

Aim: Brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) are neurotrophins—
proteins that induce the survival, development, and function of neurons. Their role in the …