Atopic dermatitis (AD) is a chronic, inflammatory skin disorder characterized by eczematous
and pruritic skin lesions. In recent decades, the prevalence of AD has increased worldwide …

The discovery in 2006 that loss-of-function mutations in the filaggrin gene (FLG) cause
ichthyosis vulgaris and can predispose to atopic dermatitis (AD) galvanized the dermatology …

Patients with atopic dermatitis (AD) have an abnormal skin barrier and are frequently
colonized by S. aureus. In this study we investigated if S. aureus penetrates the epidermal …

Atopic dermatitis (AD) is the most common chronic inflammatory skin disease. It often
precedes the development of food allergy and asthma. Recent insights into AD reveal …

The skin is the largest organ of the mammalian body. The outermost layer of mammalian
skin, the stratum corneum (SC) of the epidermis, consists of piles of dead corneocytes that …

Background Atopic dermatitis (AD) is a chronic inflammatory disease caused by the complex
interaction of genetic, immune and environmental factors. There have many recent …

Atopic dermatitis (AD) is the most common allergic skin disease in the general population. It
is a chronic inflammatory skin disease complicated by recurrent bacterial and viral infections …

Atopic dermatitis (AD) is the most common inflammatory skin disease in the industrialized
world and has multiple causes. Over the past decade, data from both experimental models …

Relentless, repetitive itching and scratching is a debilitating feature of many chronic
inflammatory skin disorders such as atopic dermatitis. While well known clinically, this itch …

abstract The skin is continuously exposed to external pathogens, and its barrier function is
critical for skin homeostasis. Previous studies have shown that the barrier dysfunction is one …