Pyrimidine ring and its fused derivatives including pyrazolo [3, 4-d] pyrimidine, pyrido [2, 3-d]
pyrimidine, quinazoline, and furo [2, 3-d] pyrimidine compounds had received much interest …

The review integrates and analyzes the published data on the chemical reactivity of α-
cyanothioacetamide, a convenient starting compound for the preparation of activated …

Eukaryotic elongation factor 2 kinase (eEF2K) is an unusual protein kinase that regulates
the elongation stage of protein synthesis by phosphorylating and inhibiting its only known …

Eukaryotic elongation factor 2 kinase (eEF2K) is a highly unusual protein kinase that
negatively regulates the elongation step of protein synthesis. This step uses the vast majority …

Abstract Pyrido [2, 3‐d] pyrimidine, a fused hetero‐bicyclic nucleus containing pyridine and
pyrimidine rings has attained the momentary attention in the sphere of multicomponent …

This review presents the advances in the use of 6-aminouracil as a starting material in the
synthesis of various heterocyclic structures such as pyrido-, pyrrolo-, and pyrimido …

Emerging advances in cancer therapy have transformed the landscape towards cancer
immunotherapy regimens. Recent discoveries have resulted in the development of clinical …

Eukaryotic elongation factor 2 kinase (eEF2K) is a key α-kinase that negatively regulates the
extension step of protein synthesis, which consumes most of the energy and amino acids …

Protein–protein interactions (PPIs), in general, are attractive yet challenging drug targets. As
a typical PPI, MTDH-SND1 interaction has recently been reported to be a promising drug …

Oncogenic activation of the mTOR signaling pathway occurs frequently in tumor cells and
contributes to the devastating features of cancer, including breast cancer. mTOR inhibitors …