Abstract N 6-methyladenosine (m 6 A), the most abundant RNA modification in eukaryotes,
plays a pivotal role in regulating many cellular and biological processes. Aberrant m 6 A …

Background—Recent exome sequencing studies identified filamin C (FLNC) as a candidate
gene for hypertrophic cardiomyopathy (HCM). Our aim was to determine the rate of FLNC …

Obesity is a risk factor of cancer. Several genes have been found to play an important role in
aetiology of obesity and tumourigenesis. Recently, some studies suggested that rs9939609 …

The NF-kappaB pathway might play a role in the pathogenesis of renal disease and type 2
diabetes (T2DM). Our aim was to determine whether common polymorphisms in NF-kappaB …

Background Single-nucleotide polymorphisms (SNPs), which are located in the first intron of
the FTO gene, are reported to be associated with body weight and the body mass index …

Mitochondrial DNA (mtDNA) differs from the nuclear genome in many aspects: a maternal
inheritance pattern; being more prone to acquire somatic de novo mutations, accumulative …

Aim: The long noncoding RNA H19 and its host micro RNA miR-675 have been found
deregulated in cardiac hypertrophy and heart failure tissues. Our aim was to investigate …

Background Fat mass and obesity-associated protein gene variants have shown diverse
influence on body weight and metabolism across different populations. Overweight, obesity …

Several common KCNQ1 gene polymorphisms have been associated with the risk of type 2
diabetes (T2DM) and diabetic nephropathy. This effect is explained by the role of the kcnq1 …

Nowadays, obesity is the greatest scourge worldwide, particularly for the developed
countries and is a huge burden for the public health. Over the past decade, GWAS have …