[HTML][HTML] Insights into antiviral mechanisms of remdesivir, lopinavir/ritonavir and chloroquine/hydroxychloroquine affecting the new SARS-CoV-2
K Uzunova, E Filipova, V Pavlova, T Vekov - Biomedicine & …, 2020 - Elsevier
Abstract Coronavirus disease 2019 (COVID-19) is a kind of viral pneumonia with an unusual
outbreak in Wuhan, China, which is caused by severe acute respiratory syndrome …
outbreak in Wuhan, China, which is caused by severe acute respiratory syndrome …
Self-consumption: the interplay of autophagy and apoptosis
G Marino, M Niso-Santano, EH Baehrecke… - … reviews Molecular cell …, 2014 - nature.com
Autophagy and apoptosis control the turnover of organelles and proteins within cells, and of
cells within organisms, respectively, and many stress pathways sequentially elicit …
cells within organisms, respectively, and many stress pathways sequentially elicit …
A comprehensive review of autophagy and its various roles in infectious, non-infectious, and lifestyle diseases: current knowledge and prospects for disease …
Autophagy (self-eating) is a conserved cellular degradation process that plays important
roles in maintaining homeostasis and preventing nutritional, metabolic, and infection …
roles in maintaining homeostasis and preventing nutritional, metabolic, and infection …
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif… - autophagy, 2021 - Taylor & Francis
In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …
Since then, this topic has received increasing attention, and many scientists have entered …
Therapeutic targeting of NF-κB in acute lung injury: a double-edged sword
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a devastating disease
that can be caused by a variety of conditions including pneumonia, sepsis, trauma, and most …
that can be caused by a variety of conditions including pneumonia, sepsis, trauma, and most …
Autophagy modulation as a potential therapeutic target for diverse diseases
Autophagy is an essential, conserved lysosomal degradation pathway that controls the
quality of the cytoplasm by eliminating protein aggregates and damaged organelles. It …
quality of the cytoplasm by eliminating protein aggregates and damaged organelles. It …
The roles of apoptosis, autophagy and unfolded protein response in arbovirus, influenza virus, and HIV infections
P Mehrbod, SR Ande, J Alizadeh, S Rahimizadeh… - Virulence, 2019 - Taylor & Francis
Virus infection induces different cellular responses in infected cells. These include cellular
stress responses like autophagy and unfolded protein response (UPR). Both autophagy and …
stress responses like autophagy and unfolded protein response (UPR). Both autophagy and …
Development of autophagy inducers in clinical medicine
Defects in autophagy have been linked to a wide range of medical illnesses, including
cancer as well as infectious, neurodegenerative, inflammatory, and metabolic diseases …
cancer as well as infectious, neurodegenerative, inflammatory, and metabolic diseases …
Angiotensin-converting enzyme 2 protects from lethal avian influenza A H5N1 infections
The potential for avian influenza H5N1 outbreaks has increased in recent years. Thus, it is
paramount to develop novel strategies to alleviate death rates. Here we show that avian …
paramount to develop novel strategies to alleviate death rates. Here we show that avian …
Anti-malaria drug chloroquine is highly effective in treating avian influenza A H5N1 virus infection in an animal model
The recent controversial studies of man-made avian flu viruses caused a media storm, and
brought new concerns to the potential of an avian influenza H5N1 virus pandemic, which …
brought new concerns to the potential of an avian influenza H5N1 virus pandemic, which …