Emerging roles of linker histones in regulating chromatin structure and function

DV Fyodorov, BR Zhou, AI Skoultchi… - Nature reviews Molecular …, 2018 - nature.com
Together with core histones, which make up the nucleosome, the linker histone (H1) is one
of the five main histone protein families present in chromatin in eukaryotic cells. H1 binds to …

[HTML][HTML] The histone variant H2A. Z in gene regulation

BD Giaimo, F Ferrante, A Herchenröther, SB Hake… - Epigenetics & …, 2019 - Springer
The histone variant H2A. Z is involved in several processes such as transcriptional control,
DNA repair, regulation of centromeric heterochromatin and, not surprisingly, is implicated in …

Chromatin and nucleosome dynamics in DNA damage and repair

MH Hauer, SM Gasser - Genes & development, 2017 - genesdev.cshlp.org
Chromatin is organized into higher-order structures that form subcompartments in
interphase nuclei. Different categories of specialized enzymes act on chromatin and …

Variants of core histones and their roles in cell fate decisions, development and cancer

M Buschbeck, SB Hake - Nature reviews Molecular cell biology, 2017 - nature.com
Histone variants endow chromatin with unique properties and show a specific genomic
distribution that is regulated by specific deposition and removal machineries. These variants …

Regulation of nucleosome dynamics by histone modifications

GE Zentner, S Henikoff - Nature structural & molecular biology, 2013 - nature.com
Chromatin is a dynamic structure that must respond to myriad stimuli to regulate access to
DNA, and chemical modification of histones is a major means by which the cell modulates …

Histone variants and epigenetics

S Henikoff, MM Smith - Cold Spring Harbor perspectives …, 2015 - cshperspectives.cshlp.org
Histones package and compact DNA by assembling into nucleosome core particles. Most
histones are synthesized at S phase for rapid deposition behind replication forks. In addition …

[HTML][HTML] Chromatin dynamics during spermiogenesis

C Rathke, WM Baarends, S Awe… - Biochimica et Biophysica …, 2014 - Elsevier
The function of sperm is to safely transport the haploid paternal genome to the egg
containing the maternal genome. The subsequent fertilization leads to transmission of a new …

Marine environmental epigenetics

JM Eirin-Lopez, HM Putnam - Annual review of marine science, 2019 - annualreviews.org
Marine organisms' persistence hinges on the capacity for acclimatization and adaptation to
the myriad of interacting environmental stressors associated with global climate change. In …

[HTML][HTML] Chromatin organization in early land plants reveals an ancestral association between H3K27me3, transposons, and constitutive heterochromatin

SA Montgomery, Y Tanizawa, B Galik, N Wang, T Ito… - Current Biology, 2020 - cell.com
Genome packaging by nucleosomes is a hallmark of eukaryotes. Histones and the pathways
that deposit, remove, and read histone modifications are deeply conserved. Yet, we lack …

[HTML][HTML] The histone variant H2A. W defines heterochromatin and promotes chromatin condensation in Arabidopsis

R Yelagandula, H Stroud, S Holec, K Zhou, S Feng… - Cell, 2014 - cell.com
Histone variants play crucial roles in gene expression, genome integrity, and chromosome
segregation. We report that the four H2A variants in Arabidopsis define different genomic …