Background—Although prospective studies, systematic reviews, and meta-analyses have
documented an association between depression and increased morbidity and mortality in a …

Objective: To assess the magnitude and direction of associations of depression with C-
reactive protein (CRP), interleukin (IL)-1, and IL-6 in community and clinical samples …

874 Circulation September 1, 2015 references are intended to be illustrative and to highlight
significant knowledge in the field. The premise underlying this scientific statement is that, at …

BACKGROUND: Major depression occurs in 4.4% to 20% of the general population. Studies
suggest that major depression is accompanied by immune dysregulation and activation of …

Increasing amounts of data suggest that inflammatory responses have an important role in
the pathophysiology of depression. Depressed patients have been found to have higher …

A large body of empirical research shows that psychosocial risk factors (PSRFs) such as low
socio-economic status, social isolation, stress, type-D personality, depression and anxiety …

Importance The etiologic factors of late-life depression are still poorly understood. Recent
evidence suggests that microvascular dysfunction is associated with depression, which may …

Depression is commonly present in patients with coronary heart disease (CHD) and is
independently associated with increased cardiovascular morbidity and mortality. Screening …

Anyone who has experienced a viral or bacterial infection knows well the feelings of
sickness, in the form of malaise, lassitude, fatigue, numbness, chills, muscle and joint aches …

Cardiovascular disease is the most common cause of morbidity and mortality globally.
Epidemiological studies using high‐sensitivity assays for serum C‐reactive protein have …