Wnt signaling plays a central regulatory role across a remarkably diverse range of functions
during embryonic development, including those involved in the formation of bone and …

Transforming growth factor-beta (TGF-β)/bone morphogenetic protein (BMP) plays a
fundamental role in the regulation of bone organogenesis through the activation of receptor …

Exosomes, nanoscale extracellular vesicles functioning as cell-to-cell communicators, are
an emerging promising therapeutic in the field of bone tissue engineering. Here, we report …

Inflammation and oxidative stress are common and co-substantial pathological processes
accompanying, promoting, and even initiating numerous cancers. The canonical WNT/β …

Runx2 is a master transcription factor for osteogenesis. The most important phenomenon
that makes this protein a master regulator for osteogenesis is its structural integrity. In …

The Wnt signaling pathway plays an important role not only in embryonic development but
also in the maintenance and differentiation of the stem cells in adulthood. In particular, Wnt …

The physiological role of microRNAs (miRNAs) in osteoblast differentiation remains elusive.
Exosomal miRNAs isolated from human bone marrow-derived mesenchymal stem cells …

Bone is one of the most dynamic organs in the body that continuously undergoes
remodeling through bone formation and resorption. A cascade of molecules and pathways …

At present, much more studies have focused on the role of microRNAs in osteoporosis, but
the more specific role of microRNA-150-3p (miR-150-3p) in osteoporosis still needs full …

Osteoblast differentiation is tightly regulated by several factors including microRNAs
(miRNAs). In this paper, we report that pre‐mir‐15b is highly expressed in differentiated …