Blood in healthy organisms is seen as a 'sterile'environment: it lacks proliferating microbes.
Dormant or not-immediately-culturable forms are not absent, however, as intracellular …

Iron is an indispensable metabolic cofactor in both pro-and eukaryotes, which engenders a
natural competition for the metal between bacterial pathogens and their human or animal …

The highly contagious disease tuberculosis (TB) is caused by the bacterium Mycobacterium
tuberculosis (Mtb), which has been evolving drug resistance at an alarming rate. Like all …

Iron acquisition is an essential aspect of cell physiology for most bacteria. Although much is
known about how bacteria initially recognize the various iron sources they can encounter …

Iron is essential for growth of Mycobacterium tuberculosis, the causative agent of
tuberculosis. To acquire iron from the host, M. tuberculosis uses the siderophores called …

Enterobactin (ENT) is a siderophore (iron-chelating compound) produced by Escherichia
coli to gain access to iron, an indispensable nutrient for bacterial growth. ENT is used as an …

To obtain essential metal ions, human pathogens secrete virulence-associated
siderophores at first and then retake the metal-chelated siderophores through a subfamily of …

Siderophores are structurally diverse, complex natural products that bind metals with
extraordinary specificity and affinity. The acquisition of iron is critical for the survival and …

Stenotrophomonas maltophilia, a Gram-negative, multi-drug-resistant bacterium, is
increasingly recognized as a key opportunistic pathogen. Thus, we embarked upon an …

Abstract Siderocalin/Lipocalin 2/Neutrophil Gelatinase Associated Lipocalin/24p3 is an
innate immune system protein with bacteriostatic activity, acting by tightly binding and …