Modeling dynamics in diseased cardiac tissue: Impact of model choice
TA Gokhale, E Medvescek… - Chaos: An Interdisciplinary …, 2017 - pubs.aip.org
Cardiac arrhythmias have been traditionally simulated using continuous models that
assume tissue homogeneity and use a relatively large spatial discretization. However, it is …
assume tissue homogeneity and use a relatively large spatial discretization. However, it is …
Simulation of ectopic pacemakers in the heart: multiple ectopic beats generated by reentry inside fibrotic regions
B Gouvêa de Barros… - BioMed research …, 2015 - Wiley Online Library
The inclusion of nonconducting media, mimicking cardiac fibrosis, in two models of cardiac
tissue produces the formation of ectopic beats. The fraction of nonconducting media in …
tissue produces the formation of ectopic beats. The fraction of nonconducting media in …
[HTML][HTML] Homogenisation for the monodomain model in the presence of microscopic fibrotic structures
Computational models in cardiac electrophysiology are notorious for long runtimes,
restricting the numbers of nodes and mesh elements in the numerical discretisations used …
restricting the numbers of nodes and mesh elements in the numerical discretisations used …
[HTML][HTML] Graph-based homogenisation for modelling cardiac fibrosis
Fibrosis, the excess of extracellular matrix, can affect, and even block, propagation of action
potential in cardiac tissue. This can result in deleterious effects on heart function, but the …
potential in cardiac tissue. This can result in deleterious effects on heart function, but the …
Simulations of Complex and Microscopic Models of Cardiac Electrophysiology Powered by Multi‐GPU Platforms
B Gouvêa de Barros, R Sachetto Oliveira… - … methods in medicine, 2012 - Wiley Online Library
Key aspects of cardiac electrophysiology, such as slow conduction, conduction block, and
saltatory effects have been the research topic of many studies since they are strongly related …
saltatory effects have been the research topic of many studies since they are strongly related …
Mind the Gap: A semicontinuum model for discrete electrical propagation in cardiac tissue
CM Costa, PAA Silva… - IEEE Transactions on …, 2015 - ieeexplore.ieee.org
Electrical propagation in cardiac tissue is a discrete or discontinuous phenomenon that
reflects the complexity of the anatomical structures and their organization in the heart, such …
reflects the complexity of the anatomical structures and their organization in the heart, such …
Multiparameter optimization of nonuniform passive diffusion properties for creating coarse-grained equivalent models of cardiac propagation
É Irakoze, V Jacquemet - Computers in biology and medicine, 2021 - Elsevier
The arrhythmogenic role of discrete cardiac propagation may be assessed by comparing
discrete (fine-grained) and equivalent continuous (coarse-grained) models. We aim to …
discrete (fine-grained) and equivalent continuous (coarse-grained) models. We aim to …
Simulation du remodelage structurel des oreillettes: dissociation endo-épicardique, optimisation multi-paramètre des conductivités et morphologie des potentiels …
E Irakoze - 2022 - papyrus.bib.umontreal.ca
La fibrillation auriculaire (FA) est le type d'arythmie cardiaque le plus fréquent. Cependant,
ses mécanismes sont encore mal compris et le développement de stratégies thérapeutiques …
ses mécanismes sont encore mal compris et le développement de stratégies thérapeutiques …
Augmentations Vs. Restoration: A Computational Study of the Effects of Bacterial Sodium Channels on Cardiac Conduction
DA Needs - 2022 - search.proquest.com
Cardiac arrhythmias, including ventricular tachycardia, ventricular fibrillation, and atrial
fibrillation, are associated with ectopic triggers such as those resulting from …
fibrillation, are associated with ectopic triggers such as those resulting from …
Bridging Scales: How Microstructural Features Impact Macroscopic Cardiac Propagation
TA Gokhale - 2018 - search.proquest.com
Cardiac arrhythmias such as atrial fibrillation and ventricular tachycardia are closely
associated with microscopic fibrotic changes in cardiac structure that result in a …
associated with microscopic fibrotic changes in cardiac structure that result in a …