Crystal engineering of pharmaceutical cocrystals in the discovery and development of improved drugs

G Bolla, B Sarma, AK Nangia - Chemical reviews, 2022 - ACS Publications
The subject of crystal engineering started in the 1970s with the study of topochemical
reactions in the solid state. A broad chemical definition of crystal engineering was published …

Ionic liquids: new forms of active pharmaceutical ingredients with unique, tunable properties

JL Shamshina, RD Rogers - Chemical Reviews, 2023 - ACS Publications
This Review aims to summarize advances over the last 15 years in the development of
active pharmaceutical ingredient ionic liquids (API-ILs), which make up a prospective game …

Biological activity of ionic liquids and their application in pharmaceutics and medicine

KS Egorova, EG Gordeev, VP Ananikov - Chemical reviews, 2017 - ACS Publications
Ionic liquids are remarkable chemical compounds, which find applications in many areas of
modern science. Because of their highly tunable nature and exceptional properties, ionic …

A review of ionic liquids: Applications towards catalytic organic transformations

RL Vekariya - Journal of Molecular Liquids, 2017 - Elsevier
Ionic liquids (ILs) have emerged as an environmentally friendly alternative to the volatile
organic solvents. ILs which are made up of cationic and anionic components can be …

The role of ionic liquids in the pharmaceutical field: An overview of relevant applications

SN Pedro, CS R. Freire, AJD Silvestre… - International journal of …, 2020 - mdpi.com
Solubility, bioavailability, permeation, polymorphism, and stability concerns associated to
solid-state pharmaceuticals demand for effective solutions. To overcome some of these …

Structure and nanostructure in ionic liquids

R Hayes, GG Warr, R Atkin - Chemical reviews, 2015 - ACS Publications
Much of chemistry is concerned with the study of reactions and processes in solution, that is,
where liquids are used as solvents. 2, 3 The solvent is the (excess) liquid phase in which …

Ionic liquids for energy, materials, and medicine

M Smiglak, JM Pringle, X Lu, L Han, S Zhang… - Chemical …, 2014 - pubs.rsc.org
As highlighted by the recent ChemComm web themed issue on ionic liquids, this field
continues to develop beyond the concept of interesting new solvents for application in the …

Ionic liquids as a potential tool for drug delivery systems

N Adawiyah, M Moniruzzaman, S Hawatulaila… - …, 2016 - pubs.rsc.org
The pharmaceutical industries face a series of challenges in the delivery of many newly
developed drug molecules because of their low solubility, bioavailability, stability and …

Ionic liquids as a useful tool for tailoring active pharmaceutical ingredients

X Wu, Q Zhu, Z Chen, W Wu, Y Lu, J Qi - Journal of Controlled Release, 2021 - Elsevier
Ionic liquids (ILs) have been widely used in biomedical and pharmaceutical fields as
solvents or permeation enhancers. Recently, more and more researchers focused on …

Recent developments on ionic liquids and deep eutectic solvents for drug delivery applications

IB Qader, K Prasad - Pharmaceutical Research, 2022 - Springer
The field of Ionic liquids (ILs) and deep eutectic solvents (DESs) is continuously expanding
due to their exceptional unique properties and highly tunable nature, which finds …