Ten years of EWAS

S Wei, J Tao, J Xu, X Chen, Z Wang, N Zhang… - Advanced …, 2021 - Wiley Online Library
Epigenome‐wide association study (EWAS) has been applied to analyze DNA methylation
variation in complex diseases for a decade, and epigenome as a research target has …

Cigarette smoke-induced alterations in blood: A review of research on DNA methylation and gene expression.

CP Silva, HM Kamens - Experimental and clinical …, 2021 - psycnet.apa.org
Worldwide, smoking remains a threat to public health, causing preventable diseases and
premature mortality. Cigarette smoke is a powerful inducer of DNA methylation and gene …

Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects

C Christiansen, JE Castillo-Fernandez… - Clinical …, 2021 - Springer
Background Smoking remains one of the leading preventable causes of death. Smoking
leaves a strong signature on the blood methylome as shown in multiple studies using the …

Identification of Smoking‐Associated Transcriptome Aberration in Blood with Machine Learning Methods

FM Huang, QL Ma, JX Ren, JR Li… - BioMed research …, 2023 - Wiley Online Library
Long‐term cigarette smoking causes various human diseases, including respiratory
disease, cancer, and gastrointestinal (GI) disorders. Alterations in gene expression and …

Education and lifestyle factors are associated with DNA methylation clocks in older African Americans

W Zhao, F Ammous, S Ratliff, J Liu, M Yu… - International journal of …, 2019 - mdpi.com
DNA methylation (DNAm) clocks are important biomarkers of cellular aging and are
associated with a variety of age-related chronic diseases and all-cause mortality. Examining …

Epigenome-wide association study and epigenetic age acceleration associated with cigarette smoking among Costa Rican adults

A Cardenas, S Ecker, RP Fadadu, K Huen, A Orozco… - Scientific Reports, 2022 - nature.com
Smoking-associated DNA methylation (DNAm) signatures are reproducible among studies
of mostly European descent, with mixed evidence if smoking accelerates epigenetic aging …

DNA methylation patterns reflect individual's lifestyle independent of obesity

I Klemp, A Hoffmann, L Müller… - Clinical and …, 2022 - Wiley Online Library
Objective Obesity is driven by modifiable lifestyle factors whose effects may be mediated by
epigenetics. Therefore, we investigated lifestyle effects on blood DNA methylation in …

[HTML][HTML] Waterpipe and cigarette epigenome analysis reveals markers implicated in addiction and smoking type inference

Z Awada, V Cahais, C Cuenin, R Akika… - Environment …, 2023 - Elsevier
Waterpipe smoking is frequent in the Middle East and Africa with emerging prevalence
worldwide. The epigenome acts as a molecular sensor to exposures and a crucial driver in …

[HTML][HTML] Targeted DNA methylation analysis and prediction of smoking habits in blood based on massively parallel sequencing

A Vidaki, BP Jiménez, B Poggiali, V Kalamara… - Forensic Science …, 2023 - Elsevier
Tobacco smoking is a frequent habit sustained by> 1.3 billion people in 2020 and the
leading preventable factor for health risk and premature mortality worldwide. In the forensic …

Association of obesity with DNA methylation age acceleration in African American mothers from the InterGEN study

C Li, Z Wang, T Hardy, Y Huang, Q Hui… - International journal of …, 2019 - mdpi.com
African American women are affected by earlier onset of age-associated health
deteriorations and obesity disproportionally, but little is known about the mechanism linking …