Ten years of EWAS
S Wei, J Tao, J Xu, X Chen, Z Wang, N Zhang… - Advanced …, 2021 - Wiley Online Library
Epigenome‐wide association study (EWAS) has been applied to analyze DNA methylation
variation in complex diseases for a decade, and epigenome as a research target has …
variation in complex diseases for a decade, and epigenome as a research target has …
Cigarette smoke-induced alterations in blood: A review of research on DNA methylation and gene expression.
Worldwide, smoking remains a threat to public health, causing preventable diseases and
premature mortality. Cigarette smoke is a powerful inducer of DNA methylation and gene …
premature mortality. Cigarette smoke is a powerful inducer of DNA methylation and gene …
Novel DNA methylation signatures of tobacco smoking with trans-ethnic effects
C Christiansen, JE Castillo-Fernandez… - Clinical …, 2021 - Springer
Background Smoking remains one of the leading preventable causes of death. Smoking
leaves a strong signature on the blood methylome as shown in multiple studies using the …
leaves a strong signature on the blood methylome as shown in multiple studies using the …
Identification of Smoking‐Associated Transcriptome Aberration in Blood with Machine Learning Methods
FM Huang, QL Ma, JX Ren, JR Li… - BioMed research …, 2023 - Wiley Online Library
Long‐term cigarette smoking causes various human diseases, including respiratory
disease, cancer, and gastrointestinal (GI) disorders. Alterations in gene expression and …
disease, cancer, and gastrointestinal (GI) disorders. Alterations in gene expression and …
Education and lifestyle factors are associated with DNA methylation clocks in older African Americans
DNA methylation (DNAm) clocks are important biomarkers of cellular aging and are
associated with a variety of age-related chronic diseases and all-cause mortality. Examining …
associated with a variety of age-related chronic diseases and all-cause mortality. Examining …
Epigenome-wide association study and epigenetic age acceleration associated with cigarette smoking among Costa Rican adults
Smoking-associated DNA methylation (DNAm) signatures are reproducible among studies
of mostly European descent, with mixed evidence if smoking accelerates epigenetic aging …
of mostly European descent, with mixed evidence if smoking accelerates epigenetic aging …
DNA methylation patterns reflect individual's lifestyle independent of obesity
I Klemp, A Hoffmann, L Müller… - Clinical and …, 2022 - Wiley Online Library
Objective Obesity is driven by modifiable lifestyle factors whose effects may be mediated by
epigenetics. Therefore, we investigated lifestyle effects on blood DNA methylation in …
epigenetics. Therefore, we investigated lifestyle effects on blood DNA methylation in …
[HTML][HTML] Waterpipe and cigarette epigenome analysis reveals markers implicated in addiction and smoking type inference
Z Awada, V Cahais, C Cuenin, R Akika… - Environment …, 2023 - Elsevier
Waterpipe smoking is frequent in the Middle East and Africa with emerging prevalence
worldwide. The epigenome acts as a molecular sensor to exposures and a crucial driver in …
worldwide. The epigenome acts as a molecular sensor to exposures and a crucial driver in …
[HTML][HTML] Targeted DNA methylation analysis and prediction of smoking habits in blood based on massively parallel sequencing
Tobacco smoking is a frequent habit sustained by> 1.3 billion people in 2020 and the
leading preventable factor for health risk and premature mortality worldwide. In the forensic …
leading preventable factor for health risk and premature mortality worldwide. In the forensic …
Association of obesity with DNA methylation age acceleration in African American mothers from the InterGEN study
African American women are affected by earlier onset of age-associated health
deteriorations and obesity disproportionally, but little is known about the mechanism linking …
deteriorations and obesity disproportionally, but little is known about the mechanism linking …