Variability in mass spectrometry-based quantification of clinically relevant drug transporters and drug metabolizing enzymes

C Wegler, FZ Gaugaz, TB Andersson… - Molecular …, 2017 - ACS Publications
Many different methods are used for mass-spectrometry-based protein quantification in
pharmacokinetics and systems pharmacology. It has not been established to what extent the …

Proteomic analysis of chicken skeletal muscle during embryonic development

H Ouyang, Z Wang, X Chen, J Yu, Z Li, Q Nie - Frontiers in physiology, 2017 - frontiersin.org
Embryonic growth and development of skeletal muscle is a major determinant of muscle
mass, and has a significant effect on meat production in chicken. To assess the protein …

DDASSQ: An open‐source, multiple peptide sequencing strategy for label free quantification based on an OpenMS pipeline in the KNIME analytics platform

M Svecla, G Garrone, F Faré, G Aletti, GD Norata… - …, 2021 - Wiley Online Library
In this study we investigated the performance of a computational pipeline for protein
identification and label free quantification (LFQ) of LC–MS/MS data sets from experimental …

Profiling the serum proteome during Schistosoma mansoni infection in the BALB/c mice: A focus on the altered lipid metabolism as a key modulator of host-parasite …

G Gonçalves-Silva, LGMS Vieira… - Frontiers in …, 2022 - frontiersin.org
Schistosomiasis represents a condition in which every aspect of the disease, starting from
skin invasion of the cercariae to egg laying by adult worms, incites a tissue response from …

Proteomic analysis of inhibitor of apoptosis protein‑like protein‑2 on breast cancer cell proliferation

S Xiang, L Zhu, Z Zhang, S Wang… - Molecular …, 2022 - spandidos-publications.com
Although inhibitor of apoptosis protein‑like protein‑2 (ILP‑2) is considered to be a novel
enhancer of breast cancer proliferation, its underlying mechanism of action remains …

PROTEOMIC ANALYSIS OF TAENIA SOLIUM CYST FLUID BY SHOTGUN LC-MS/MS

Y Cui, X Wang, J Xu, X Liu, X Wang… - The Journal of …, 2021 - meridian.allenpress.com
Taenia solium cysts were collected from pig skeletal muscle and analyzed via a shotgun
proteomic approach to identify known proteins in the cyst fluid and to explore host-parasite …

Schistosoma mansoni infection induces hepatic metallothionein and S100 protein expression alongside metabolic dysfunction in hamsters

P Ghezellou, V von Bülow, D Luh, E Badin… - PNAS …, 2024 - academic.oup.com
Schistosomiasis, a widespread neglected tropical disease, presents a complex and
multifaceted clinical-pathological profile. Using hamsters as final hosts, we dissected …

Understanding global changes of the mouse brain proteome after vaginal infection with HSV-2 using a label-free shotgun approach

J Cheng, Q Wang, Y Hu, T Mou, J Wang… - Frontiers in Cellular …, 2022 - frontiersin.org
Herpes simplex virus type 2 (HSV-2) is a common human pathogen that establishes lifelong
latency in neurons of the nervous system. The number of severe central nervous system …

The schistosomiasis spleenOME: Unveiling the proteomic landscape of splenomegaly using label-free mass spectrometry

M Cosenza-Contreras, RA Oliveira e Castro… - Frontiers in …, 2019 - frontiersin.org
Schistosomiasis is a neglected parasitic disease that affects millions of people worldwide
and is caused by helminth parasites from the genus Schistosoma. When caused by S …

Alterations in the proteomic composition of Serratia marcescens in response to manganese (II)

PS Queiroz, FAD Ruas, NR Barboza… - BMC …, 2018 - Springer
Background Proteomics is an important tool for the investigation of dynamic physiological
responses of microbes under heavy metal stress. To gain insight into how bacteria respond …