[HTML][HTML] Increased mesenchymal stem cell functionalization in three-dimensional manufacturing settings for enhanced therapeutic applications
D Kouroupis, D Correa - Frontiers in bioengineering and …, 2021 - frontiersin.org
Mesenchymal stem/stromal cell (MSC) exist within their in vivo niches as part of
heterogeneous cell populations, exhibiting variable stemness potential and supportive …
heterogeneous cell populations, exhibiting variable stemness potential and supportive …
[HTML][HTML] Combining stem cells and biomaterial scaffolds for constructing tissues and cell delivery
SM Willerth, SE Sakiyama-Elbert - StemJournal, 2019 - content.iospress.com
Combining stem cells with biomaterial scaffolds serves as a promising strategy for
engineering tissues for both in vitro and in vivo applications. This updated review details …
engineering tissues for both in vitro and in vivo applications. This updated review details …
Hydrogel mechanics are a key driver of bone formation by mesenchymal stromal cell spheroids
J Whitehead, KH Griffin, M Gionet-Gonzales… - Biomaterials, 2021 - Elsevier
Mesenchymal stromal cells (MSCs) can promote tissue repair in regenerative medicine, and
their therapeutic potential is further enhanced via spheroid formation. Stress relaxation of …
their therapeutic potential is further enhanced via spheroid formation. Stress relaxation of …
Fabrication techniques of biomimetic scaffolds in three‐dimensional cell culture: A review
AK Badekila, S Kini, AK Jaiswal - Journal of cellular physiology, 2021 - Wiley Online Library
In the last four decades, several researchers worldwide have routinely and meticulously
exercised cell culture experiments in two‐dimensional (2D) platforms. Using traditionally …
exercised cell culture experiments in two‐dimensional (2D) platforms. Using traditionally …
Engineered Cell‐Secreted Extracellular Matrix Modulates Cell Spheroid Mechanosensing and Amplifies Their Response to Inductive Cues for the Formation of …
T Gonzalez‐Fernandez, AJ Tenorio… - Advanced …, 2022 - Wiley Online Library
The clinical translation of mesenchymal stromal cell (MSC)‐based therapies remains
challenging due to rapid cell death and poor control over cell behavior. Compared to …
challenging due to rapid cell death and poor control over cell behavior. Compared to …
Mesenchymal stem cell spheroids embedded in an injectable thermosensitive hydrogel: an in situ drug formation platform for accelerated wound healing
MA Nilforoushzadeh, M Khodadadi Yazdi… - ACS biomaterials …, 2020 - ACS Publications
The ability of mesenchymal stem cells (MSCs) to enhance cutaneous wound healing has
been well established. Extensive expansion of cells to reach sufficient cell numbers for …
been well established. Extensive expansion of cells to reach sufficient cell numbers for …
[HTML][HTML] Mesenchymal stem cell 3D encapsulation technologies for biomimetic microenvironment in tissue regeneration
Mesenchymal stem cell (MSC) encapsulation technique has long been emerged in tissue
engineering as it plays an important role in implantation of stem cells to regenerate a …
engineering as it plays an important role in implantation of stem cells to regenerate a …
[HTML][HTML] Hydrogel degradation promotes angiogenic and regenerative potential of cell spheroids for wound healing
Chronic nonhealing wounds are debilitating and diminish one's quality of life, necessitating
the development of improved strategies for effective treatment. Biomaterial-and cell-based …
the development of improved strategies for effective treatment. Biomaterial-and cell-based …
Multifactorial experimental design to optimize the anti-inflammatory and proangiogenic potential of mesenchymal stem cell spheroids
KC Murphy, J Whitehead, PC Falahee, D Zhou… - Stem Cells, 2017 - academic.oup.com
Mesenchymal stem cell therapies promote wound healing by manipulating the local
environment to enhance the function of host cells. Aggregation of mesenchymal stem cells …
environment to enhance the function of host cells. Aggregation of mesenchymal stem cells …
Alginate microspheres-collagen hydrogel, as a novel 3D culture system, enhanced skin wound healing of hUCMSCs in rats model
Y Gao, Y Kang, T Wang, C Li, S Shen, C Qu… - Colloids and Surfaces B …, 2022 - Elsevier
While stem cell transplantation has emerged as a promising approach to improving wound
healing outcomes, the application of stem cells to date has been limited by the poor survival …
healing outcomes, the application of stem cells to date has been limited by the poor survival …