Ferrocene is an important structural core in bioorganometallic chemistry because of its
inherent stability, excellent redox properties, and low toxicity. Ferroquine and ferrocifen are …

Cancer is one of the most fatal threatens to human health throughout the world. The major
challenges in the control and eradication of cancers are the continuous emergency of drug …

Ferrocene has been the most used organometallic moiety introduced in organic and
bioinorganic drugs to cure cancers and various other diseases. Following several …

Resistance to chemotherapy is a current clinical problem, especially in the treatment of
microbial infections and cancer. One strategy to overcome this is to make new derivatives of …

Introduction Cancer continues to be a big threat and its treatment is a huge challenge
among the medical fraternity. Conventional anti-cancer agents are losing their efficiency …

Secondary natural products are a source of an endless inspiration in medicinal chemistry.
They are characterized by a complex structure and potent biological activity. Ferrocene is an …

During recent years, accumulating evidence suggested that metal‐based candidate drugs
are promising modulators of cytoskeletal and cytoskeleton‐associated proteins. This was …

Ispinesib is a potent inhibitor of kinesin spindle protein (KSP), which has been identified as a
promising target for antimitotic anticancer drugs. Herein, we report the synthesis of half …

Antimitotic agents are among the most important drugs used in anticancer therapy. Kinesin
spindle protein (KSP) was proposed as a promising target for new antimitotic drugs. Herein …

The incorporation of the ferrocenyl moiety into a bioactive molecule may significantly alter
the activity of the resulting conjugate. By applying this strategy, we designed ferrocenyl …