Metaplasia is the replacement of one differentiated somatic cell type with another
differentiated somatic cell type in the same tissue. Typically, metaplasia is triggered by …

Insights into the stem cell niche have allowed researchers to cultivate adult tissue stem cells
as organoids that display structural and phenotypic features of healthy and diseased …

Today, the rapid development of science and technology and the rapid change in economy
and society are changing the way of life of human beings and affecting the natural, living …

Esophageal cancer (EC) has been a leading cause of cancer death worldwide in part due to
late detection and lack of precision treatment. EC includes two major malignancies …

Objective Barrett's oesophagus is a premalignant condition that occurs in the context of
gastro-oesophageal reflux. However, most Barrett's cases are undiagnosed because of …

Esophageal cancer (EC) is one of the most lethal cancers and a public health concern
worldwide, owing to late diagnosis and lack of efficient treatment. Esophageal squamous …

The aberrant DNA methylation of tumor suppressor genes is well documented in
esophageal cancer, including adenocarcinoma (EAC) and squamous cell carcinoma …

NTRK3 is a member of the neurotrophin receptor family and regulates cell survival. It
appears to be a dependence receptor, and thus has the potential to act as an oncogene or …

Genetic and Epigenetic Alterations in Barrett’s Esophagus and Esophageal Adenocarcinoma -
Gastroenterology Clinics Skip to Main Content Skip to Main Menu Advertisement …

Cancer development is a dynamic evolutionary process characterized by marked
intratumoural heterogeneity at the genetic, epigenetic and phenotypic levels. Barrett …