Prescribing of opioid analgesics and buprenorphine for opioid use disorder during the COVID-19 pandemic

JM Currie, MK Schnell, H Schwandt… - JAMA network open, 2021 - jamanetwork.com
Importance The COVID-19 pandemic disrupted medical care, impacting prescribing of
opioid analgesics and buprenorphine for opioid use disorder. Understanding these patterns …

Balancing the risks and benefits of benzodiazepines

ME Hirschtritt, M Olfson, K Kroenke - Jama, 2021 - jamanetwork.com
In September 2020, the US Food and Drug Administration (FDA) announced an anticipated
update to the boxed warning on all benzodiazepines to explicitly “address the serious risks …

Understanding the rise in overdose deaths involving opioids and non-opioid prescription drugs in the United States

D Powell, ED Peet, RL Pacula - International Journal of Drug Policy, 2023 - Elsevier
Background Previous studies demonstrate that the reformulation of OxyContin in the US in
2010 induced substitution to illicit opioids, causing illicit opioid markets to grow …

The risk of overdose with concomitant use of Z-drugs and prescription opioids: a population-based cohort study

A Szmulewicz, BT Bateman, R Levin… - American Journal of …, 2021 - Am Psychiatric Assoc
Objective: The Z-drugs (zolpidem, zopiclone, zaleplon) are widely used to treat insomnia in
patients receiving prescription opioids, and the risk of overdose resulting from this …

Trends in emergency department visits for unsupervised pediatric medication exposures

MC Lovegrove, NJ Weidle, AI Geller, JN Lind… - American journal of …, 2023 - Elsevier
Introduction Emergency department visits and hospitalizations for unsupervised medication
exposures among young children increased in the early 2000s. Prevention efforts were …

Comparison of opioids prescribed for patients at risk for opioid misuse before and after publication of the centers for disease control and prevention's opioid …

JF Scherrer, J Tucker, J Salas, Z Zhang… - JAMA Network …, 2020 - jamanetwork.com
Importance It is not known whether decreases in Schedule II (high abuse potential) vs
Schedule IV (lower abuse potential) opioid prescriptions overall and among high-risk …

Application of a diazepam milligram equivalency algorithm to assess benzodiazepine dose intensity in Rhode Island in 2018

EP Borrelli, J Bratberg, BD Hallowell… - Journal of Managed …, 2022 - jmcp.org
BACKGROUND: Benzodiazepines are indicated for the treatment of many conditions, such
as anxiety disorders, muscle spasms, alcohol withdrawal, agitation, movement disorders …

Sex differences in US emergency department non-fatal visits for benzodiazepine poisonings in adolescents and young adults

GA Bushnell, M Olfson, SS Martins - Drug and alcohol dependence, 2021 - Elsevier
Background Benzodiazepine (BZD)-related overdose deaths have risen in the past decade
and BZD misuse contributes to thousands of emergency department (ED) visits annually …

Benzodiazepine use among Medicare, commercially insured, and veteran older adults, 2013–2017

DT Maust, HM Kim, IR Wiechers… - Journal of the …, 2021 - Wiley Online Library
BACKGROUND/OBJECTIVES Benzodiazepines (BZDs) are widely prescribed to older
adults. Although prescribing has declined in the US Department of Veterans Affairs (VA) …

FDALabel for drug repurposing studies and beyond

H Fang, S Harris, Z Liu, S Thakkar, J Yang… - Nature …, 2020 - nature.com
To the Editor—Prescription drug labeling (also known as the package insert or prescribing
information) accompanies every US Food and Drug Administration (FDA)-approved …