Antibody vectors for imaging

T Olafsen, AM Wu - Seminars in nuclear medicine, 2010 - Elsevier
Noninvasive molecular imaging approaches include nuclear, optical, magnetic resonance
imaging, computed tomography, ultrasound, and photoacoustic imaging, which require …

Radionuclide-based cancer imaging targeting the carcinoembryonic antigen

H Hong, J Sun, W Cai - Biomarker insights, 2008 - journals.sagepub.com
Carcinoembryonic antigen (CEA), highly expressed in many cancer types, is an important
target for cancer diagnosis and therapy. Radionuclide-based imaging techniques (gamma …

Architecture effects on the binding of cholera toxin by helical glycopolypeptides

S Liu, KL Kiick - Macromolecules, 2008 - ACS Publications
A variety of binding events in biological systems are mediated by multivalent interactions
between oligosaccharides and saccharide receptors present on pathogens and cell …

Affinity maturation and fine functional mapping of an antibody fragment against a novel neutralizing epitope on human vascular endothelial growth factor

H Lamdan, JV Gavilondo, Y Muñoz, A Pupo… - Molecular …, 2013 - pubs.rsc.org
We have previously reported the isolation of a novel single-chain variable fragment (scFv)
against vascular endothelial growth factor (VEGF), from a phage-displayed human antibody …

Immunogenicity and some safety features of a VEGF-based cancer therapeutic vaccine in rats, rabbits and non-human primates

Y Morera, M Bequet-Romero, M Ayala, JC Velazco… - Vaccine, 2010 - Elsevier
We have developed a cancer vaccine candidate (hereafter denominated CIGB-247), based
on recombinant modified human vascular endothelial growth factor (VEGF) as antigen, and …

Antibodies in single-chain format against tumour-associated antigens: present and future applications

L Accardi, P Di Bonito - Current medicinal chemistry, 2010 - ingentaconnect.com
The recombinant antibodies in single-chain format (scFv) have found broad applications in
both therapeutic and diagnostic fields. Tumour-associated antigens (TAAs) are proteins or …

Selection of phage-displayed human antibody fragments on Dengue virus particles captured by a monoclonal antibody: application to the four serotypes

S Cabezas, G Rojas, A Pavon, M Alvarez… - Journal of Virological …, 2008 - Elsevier
Antibody fragments to the four Dengue virus serotypes were isolated from a human
universal naïve library using phage display technology. Phage-displayed antibody …

Rapid detection of hepatitis B virus surface antigen by an agglutination assay mediated by a bispecific diabody against both human erythrocytes and hepatitis B virus …

YP Chen, YY Qiao, XH Zhao, HS Chen… - Clinical and Vaccine …, 2007 - Am Soc Microbiol
Bispecific antibodies have immense potential for use in clinical applications. In the present
study, a bispecific diabody against human red blood cells (RBCs) and hepatitis B virus …

Phase I Clinical Trial of the 131I-Labeled Anticarcinoembryonic Antigen CIGB-M3 Multivalent Antibody Fragment

GP González, IG García, JG González… - Cancer Biotherapy & …, 2011 - liebertpub.com
Abstract Center for Genetic Engineering and Biotechnology (CIGB)-M3 is a trivalent
recombinant single-chain Fv antibody fragment specific for carcinoembryonic antigen (CEA) …

[HTML][HTML] 抗人大肠癌双价单链抗体基因的构建及表达

严丹丹, 杨福辉, 方瑾 - 世界华人消化杂志, 2006 - wjgnet.com
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