Extracellular nucleotides and P2 receptors in renal function

V Vallon, R Unwin, EW Inscho… - Physiological …, 2020 - journals.physiology.org
The understanding of the nucleotide/P2 receptor system in the regulation of renal
hemodynamics and transport function has grown exponentially over the last 20 yr. This …

Purinergic signalling in the kidney in health and disease

G Burnstock, LC Evans, MA Bailey - Purinergic signalling, 2014 - Springer
The involvement of purinergic signalling in kidney physiology and pathophysiology is rapidly
gaining recognition and this is a comprehensive review of early and recent publications in …

Blood pressure responses to renal denervation precede and are independent of the sympathetic and baroreflex effects

G Grassi, G Seravalle, G Brambilla, D Trabattoni… - …, 2015 - Am Heart Assoc
It is still largely unknown whether the neuroadrenergic responses to renal denervation (RD)
are involved in its blood pressure (BP)–lowering effects and represent predictors of the BP …

[HTML][HTML] Resolving the ionotropic P2X4 receptor mystery points towards a new therapeutic target for cardiovascular diseases

B Bragança, P Correia-de-Sá - International Journal of Molecular …, 2020 - mdpi.com
Adenosine triphosphate (ATP) is a primordial versatile autacoid that changes its role from an
intracellular energy saver to a signaling molecule once released to the extracellular milieu …

Renal neurohormonal regulation in heart failure decompensation

S Jönsson, MB Agic, F Narfström… - American Journal …, 2014 - journals.physiology.org
Decompensation in heart failure occurs when the heart fails to balance venous return with
cardiac output, leading to fluid congestion and contributing to mortality. Decompensated …

[HTML][HTML] Activation of P2X7 Receptor Mediates the Abnormal Ovulation Induced by Chronic Restraint Stress and Chronic Cold Stress

X Fan, J Wang, Y Ma, D Chai, S Han, C Xiao, Y Huang… - Biology, 2024 - mdpi.com
Simple Summary Chronic stress significantly impacts physical and mental health and has
also been shown to affect female reproduction, but the underlying mechanisms are not well …

[HTML][HTML] Neuroimmune system-mediated renal protection mechanisms

T Inoue - Clinical and Experimental Nephrology, 2021 - Springer
The autonomic nervous system plays an important role in maintaining homeostasis in
organisms. Recent studies have shown that it also controls inflammation by directly altering …

[HTML][HTML] Role of the renal sympathetic nerves in renal sodium/potassium handling and renal damage in spontaneously hypertensive rats

J Li, Q He, W Wu, Q Li, R Huang… - Experimental and …, 2016 - spandidos-publications.com
Renal sympathetic nerve activity has an important role in renal disease-associated
hypertension and in the modulation of fluid homeostasis. In the present study, changes in …

Renal denervation inhibits the renin–angiotensin–aldosterone system in spontaneously hypertensive rats

F Qin, J Li, YF Dai, X Zhong, Y Pan - Clinical and Experimental …, 2022 - Taylor & Francis
This study was conducted to explore the effect of renal denervation (RDN) on the renin–
angiotensin–aldosterone system (RAAS) in spontaneously hypertensive rats (SHRs). Our …

Renal denervation and hypertension-The need to investigate unintended effects and neural control of the human kidney

O Grisk - Autonomic Neuroscience, 2017 - Elsevier
Increased renal sympathetic nerve activity (RSNA) is present in human and experimental
forms of arterial hypertension. Experimental denervation studies showed that renal nerves …